Gut and Liver is an international journal of gastroenterology, focusing on the gastrointestinal tract, liver, biliary tree, pancreas, motility, and neurogastroenterology. Gut atnd Liver delivers up-to-date, authoritative papers on both clinical and research-based topics in gastroenterology. The Journal publishes original articles, case reports, brief communications, letters to the editor and invited review articles in the field of gastroenterology. The Journal is operated by internationally renowned editorial boards and designed to provide a global opportunity to promote academic developments in the field of gastroenterology and hepatology. +MORE
Yong Chan Lee |
Professor of Medicine Director, Gastrointestinal Research Laboratory Veterans Affairs Medical Center, Univ. California San Francisco San Francisco, USA |
Jong Pil Im | Seoul National University College of Medicine, Seoul, Korea |
Robert S. Bresalier | University of Texas M. D. Anderson Cancer Center, Houston, USA |
Steven H. Itzkowitz | Mount Sinai Medical Center, NY, USA |
All papers submitted to Gut and Liver are reviewed by the editorial team before being sent out for an external peer review to rule out papers that have low priority, insufficient originality, scientific flaws, or the absence of a message of importance to the readers of the Journal. A decision about these papers will usually be made within two or three weeks.
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The final responsibility for the decision to accept or reject lies with the editors. In many cases, papers may be rejected despite favorable reviews because of editorial policy or a lack of space. The editor retains the right to determine publication priorities, the style of the paper, and to request, if necessary, that the material submitted be shortened for publication.
Hye-Won Park*, Jeong-Sik Byeon*, Suk-Kyun Yang*, Hyun Soo Kim†, Won Ho Kim‡, Tae Il Kim‡, Dong Il Park§, Young-Ho Kim§, Hyo Jong Kim∥, Moon Sung Lee¶, Il-Kwon Chung¶, Sung-Ae Jung#, Yoon Tae Jeen**, Jai Hyun Choi**, Hwang Choi††, Kyu Yong Choi††, Dong Soo Han‡‡, and Jae Suk Song§§
Correspondence to: Jeong-Sik Byeon
Gut Liver 2009;3(1):35-40. https://doi.org/10.5009/gnl.2009.3.1.35
Published online November 30, -0001, Published date March 30, 2009
Copyright © Gut and Liver.
Background/Aims: The incidence of colorectal cancer is increasing in Korea, but the epidemiology of colorectal neoplasm is not clearly defined. We aimed to elucidate the prevalence of colorectal neoplasm in average-risk Koreans and explore the underlying risk factors. Methods: A large-scale, multicenter, prospective study was conducted. Of the 19,460 subjects who underwent colonoscopy at 11 university hospitals, we analyzed 3,951 consecutive asymptomatic adults with no risk factors for colorectal cancer. Results: The subjects were aged 52.1±11.6 years (mean±SD) and 60.1% of them were men. The prevalences of colorectal neoplasm and advanced neoplasm were 33.3% and 2.2%, respectively. The prevalence of a neoplasm increased with age (trend: p<0.001) and was higher in males (p<0.001). The prevalence of a proximal neoplasm was higher in subjects with a distal neoplasm than in those without a distal neoplasm (11.9% vs. 5.4%, p<0.001). However, 150 (52.1%) of the 288 subjects with a proximal neoplasm had no distal neoplasm. Conclusions: The overall prevalence of colorectal neoplasm in asymptomatic average-risk Koreans is comparable with that in Western countries. Being male and older are associated with a higher risk of colorectal neoplasm. Over half of proximal neoplasms are not associated with any distal sentinel lesions. (Gut and Liver 2009;3:35-40)
Keywords: Prevalence, Colonoscopy, Colorectal neoplasms, Korea, Mass screening
Gut and Liver 2009; 3(1): 35-40
Published online March 30, 2009 https://doi.org/10.5009/gnl.2009.3.1.35
Copyright © Gut and Liver.
Hye-Won Park*, Jeong-Sik Byeon*, Suk-Kyun Yang*, Hyun Soo Kim†, Won Ho Kim‡, Tae Il Kim‡, Dong Il Park§, Young-Ho Kim§, Hyo Jong Kim∥, Moon Sung Lee¶, Il-Kwon Chung¶, Sung-Ae Jung#, Yoon Tae Jeen**, Jai Hyun Choi**, Hwang Choi††, Kyu Yong Choi††, Dong Soo Han‡‡, and Jae Suk Song§§
Department of Internal Medicine, *Asan Medical Center, University of Ulsan College of Medicine, Seoul, †Yonsei University Wonju College of Medicine, Wonju, ‡Yonsei University College of Medicine, Seoul, §Sungkyunkwan University College of Medicine, Seoul, ∥Kyunghee University College of Medicine, Seoul, ¶Soonchunhyang University College of Medicine, Bucheon and Cheonan, #Ewha Woman's University College of Medicine, Seoul, **Korea University College of Medicine, Seoul and Ansan, ††The Catholic University College of Medicine, Incheon, ‡‡Hanyang University College of Medicine, Guri, and §§Department of Preventive Medicine, Kwandong University College of Medicine, Gangneung, Korea
Correspondence to:Jeong-Sik Byeon
Background/Aims: The incidence of colorectal cancer is increasing in Korea, but the epidemiology of colorectal neoplasm is not clearly defined. We aimed to elucidate the prevalence of colorectal neoplasm in average-risk Koreans and explore the underlying risk factors. Methods: A large-scale, multicenter, prospective study was conducted. Of the 19,460 subjects who underwent colonoscopy at 11 university hospitals, we analyzed 3,951 consecutive asymptomatic adults with no risk factors for colorectal cancer. Results: The subjects were aged 52.1±11.6 years (mean±SD) and 60.1% of them were men. The prevalences of colorectal neoplasm and advanced neoplasm were 33.3% and 2.2%, respectively. The prevalence of a neoplasm increased with age (trend: p<0.001) and was higher in males (p<0.001). The prevalence of a proximal neoplasm was higher in subjects with a distal neoplasm than in those without a distal neoplasm (11.9% vs. 5.4%, p<0.001). However, 150 (52.1%) of the 288 subjects with a proximal neoplasm had no distal neoplasm. Conclusions: The overall prevalence of colorectal neoplasm in asymptomatic average-risk Koreans is comparable with that in Western countries. Being male and older are associated with a higher risk of colorectal neoplasm. Over half of proximal neoplasms are not associated with any distal sentinel lesions. (Gut and Liver 2009;3:35-40)
Keywords: Prevalence, Colonoscopy, Colorectal neoplasms, Korea, Mass screening