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  • 1. Aims and Scope

    Gut and Liver is an international journal of gastroenterology, focusing on the gastrointestinal tract, liver, biliary tree, pancreas, motility, and neurogastroenterology. Gut atnd Liver delivers up-to-date, authoritative papers on both clinical and research-based topics in gastroenterology. The Journal publishes original articles, case reports, brief communications, letters to the editor and invited review articles in the field of gastroenterology. The Journal is operated by internationally renowned editorial boards and designed to provide a global opportunity to promote academic developments in the field of gastroenterology and hepatology. +MORE

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    Editor-in-Chief
    Yong Chan Lee Professor of Medicine
    Director, Gastrointestinal Research Laboratory
    Veterans Affairs Medical Center, Univ. California San Francisco
    San Francisco, USA

    Deputy Editor

    Deputy Editor
    Jong Pil Im Seoul National University College of Medicine, Seoul, Korea
    Robert S. Bresalier University of Texas M. D. Anderson Cancer Center, Houston, USA
    Steven H. Itzkowitz Mount Sinai Medical Center, NY, USA
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    All papers submitted to Gut and Liver are reviewed by the editorial team before being sent out for an external peer review to rule out papers that have low priority, insufficient originality, scientific flaws, or the absence of a message of importance to the readers of the Journal. A decision about these papers will usually be made within two or three weeks.
    The remaining articles are usually sent to two reviewers. It would be very helpful if you could suggest a selection of reviewers and include their contact details. We may not always use the reviewers you recommend, but suggesting reviewers will make our reviewer database much richer; in the end, everyone will benefit. We reserve the right to return manuscripts in which no reviewers are suggested.

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Original Article

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Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Diagnosis of Pancreatic and Peripancreatic Lesions: A Single Center Experience in Korea

Chang Yun Hwang, Sang Soo Lee*, Tae Jun Song, Sung-Hoon Moon, Don Lee, Do Hyun Park, Dong Wan Seo, Sung Koo Lee, and Myung-Hwan Kim

Division of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Correspondence to: Sang Soo Lee. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 388-1, Pungnap 2-dong, Songpa-gu, Seoul 138-736, Korea. Tel: +82-2-3010-3187, Fax: +82-2-485-5782, ssleedr@amc.seoul.kr

Received: February 12, 2009; Accepted: April 26, 2009

Gut Liver 2009; 3(2): 116-121

Published online July 1, 2009 https://doi.org/10.5009/gnl.2009.3.2.116

Copyright © Gut and Liver.

Abstract

Background/Aims

Although endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use has been increasing in Korea, there have not been many reports about its performance. The aim of this study was to assess the utility of EUS-FNA without on-site cytopathologist in establishing the diagnosis of solid pancreatic and peripancreatic masses from a single institution in Korea.

Methods

Medical records of 139 patients who underwent EUS-FNA for pancreatic and peripancreatic solid mass in the year 2007, were retrospectively reviewed. By comparing cytopathologic diagnosis of FNA with final diagnosis, sensitivity, specificity, and accuracy were determined, and factors influencing the accuracy as well as complications were analyzed.

Results

One hundred twenty out of 139 cases had final diagnosis of malignancy. Sensitivity, specificity, and accuracy of EUS-FNA were 82%, 89%, and 83%, respectively, and positive and negative predictive values were 100% and 46%, respectively. As for factors influencing the accuracy of FNA, lesion size was marginally significant (p-value 0.08) by multivariate analysis.

Conclusions

EUS-FNA performed without on-site cytopathologist was found to be accurate and safe, and thus EUS-FNA should be a part of the standard management algorithm for pancreatic and peripancreatic mass.

Keywords: EUS-FNA, Pancreatic neoplasms, Peripancreatic mass, Diagnostic accuracy


Article

Original Article

Gut Liver 2009; 3(2): 116-121

Published online July 1, 2009 https://doi.org/10.5009/gnl.2009.3.2.116

Copyright © Gut and Liver.

Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Diagnosis of Pancreatic and Peripancreatic Lesions: A Single Center Experience in Korea

Chang Yun Hwang, Sang Soo Lee*, Tae Jun Song, Sung-Hoon Moon, Don Lee, Do Hyun Park, Dong Wan Seo, Sung Koo Lee, and Myung-Hwan Kim

Division of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Correspondence to: Sang Soo Lee. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 388-1, Pungnap 2-dong, Songpa-gu, Seoul 138-736, Korea. Tel: +82-2-3010-3187, Fax: +82-2-485-5782, ssleedr@amc.seoul.kr

Received: February 12, 2009; Accepted: April 26, 2009

Abstract

Background/Aims

Although endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use has been increasing in Korea, there have not been many reports about its performance. The aim of this study was to assess the utility of EUS-FNA without on-site cytopathologist in establishing the diagnosis of solid pancreatic and peripancreatic masses from a single institution in Korea.

Methods

Medical records of 139 patients who underwent EUS-FNA for pancreatic and peripancreatic solid mass in the year 2007, were retrospectively reviewed. By comparing cytopathologic diagnosis of FNA with final diagnosis, sensitivity, specificity, and accuracy were determined, and factors influencing the accuracy as well as complications were analyzed.

Results

One hundred twenty out of 139 cases had final diagnosis of malignancy. Sensitivity, specificity, and accuracy of EUS-FNA were 82%, 89%, and 83%, respectively, and positive and negative predictive values were 100% and 46%, respectively. As for factors influencing the accuracy of FNA, lesion size was marginally significant (p-value 0.08) by multivariate analysis.

Conclusions

EUS-FNA performed without on-site cytopathologist was found to be accurate and safe, and thus EUS-FNA should be a part of the standard management algorithm for pancreatic and peripancreatic mass.

Keywords: EUS-FNA, Pancreatic neoplasms, Peripancreatic mass, Diagnostic accuracy

Table 1 Baseline Patient and Lesion Characteristics


Table 2 Diagnostic Categories Compared between FNA and Final Diagnosis for Malignant Disease

FNA, fine needle aspiration.

*Stomach cancer (1), MUO (1).


Table 3 Diagnostic Categories Compared between FNA and Final Diagnosis for Benign Disease

FNA, fine needle aspiration.

*Includes one case of autoimmune pancreatitis.


Table 4 Utility of EUS-FNA in Establishing the Diagnosis of Solid Pancreatic and Peripancreatic Lesions

EUS-FNA, endoscopic ultrasound guided fine needle aspiration.


Table 5 Analysis of Factors Having Influence on the Accuracy of EUS-FNA

EUS-FNA, endoscopic ultrasound guided fine needle aspiration.

*Included variables were location, size, and needle type; n=126.


Gut and Liver

Vol.15 No.6
November, 2021

pISSN 1976-2283
eISSN 2005-1212

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