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  • 1. Aims and Scope

    Gut and Liver is an international journal of gastroenterology, focusing on the gastrointestinal tract, liver, biliary tree, pancreas, motility, and neurogastroenterology. Gut atnd Liver delivers up-to-date, authoritative papers on both clinical and research-based topics in gastroenterology. The Journal publishes original articles, case reports, brief communications, letters to the editor and invited review articles in the field of gastroenterology. The Journal is operated by internationally renowned editorial boards and designed to provide a global opportunity to promote academic developments in the field of gastroenterology and hepatology. +MORE

  • 2. Editorial Board

    Editor-in-Chief + MORE

    Editor-in-Chief
    Yong Chan Lee Professor of Medicine
    Director, Gastrointestinal Research Laboratory
    Veterans Affairs Medical Center, Univ. California San Francisco
    San Francisco, USA

    Deputy Editor

    Deputy Editor
    Jong Pil Im Seoul National University College of Medicine, Seoul, Korea
    Robert S. Bresalier University of Texas M. D. Anderson Cancer Center, Houston, USA
    Steven H. Itzkowitz Mount Sinai Medical Center, NY, USA
  • 3. Editorial Office
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  • 5. Instructions for Authors
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  • 7. Ethical Standards
  • 8. Peer Review

    All papers submitted to Gut and Liver are reviewed by the editorial team before being sent out for an external peer review to rule out papers that have low priority, insufficient originality, scientific flaws, or the absence of a message of importance to the readers of the Journal. A decision about these papers will usually be made within two or three weeks.
    The remaining articles are usually sent to two reviewers. It would be very helpful if you could suggest a selection of reviewers and include their contact details. We may not always use the reviewers you recommend, but suggesting reviewers will make our reviewer database much richer; in the end, everyone will benefit. We reserve the right to return manuscripts in which no reviewers are suggested.

    The final responsibility for the decision to accept or reject lies with the editors. In many cases, papers may be rejected despite favorable reviews because of editorial policy or a lack of space. The editor retains the right to determine publication priorities, the style of the paper, and to request, if necessary, that the material submitted be shortened for publication.

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Cross-Regulation of Innate and Adaptive Immunity: A New Perspective for the Pathogenesis of Inflammatory Bowel Disease

Da Yeon Oh, and Seong-Joon Koh

Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Korea

Correspondence to: Seong-Joon Koh, Division of Gastroenterology & Hepatology, Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 156-707, Korea, Tel: +82-2-870-2234, Fax: +82-2-870-3866, E-mail: jel1206@snu.ac.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Gut Liver 2015;9(3):263-264. https://doi.org/10.5009/gnl15123

Published online May 15, 2015, Published date May 31, 2015

Copyright © Gut and Liver.

References

  1. Baumgart, DC, Sandborn, WJ. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet, 2007;369;1641-1657.
    Pubmed CrossRef
  2. Han, DS. Current status and prospects of intestinal microbiome studies. Intest Res, 2014;12;178-183.
    Pubmed KoreaMed CrossRef
  3. Fuss, IJ, Neurath, M, Boirivant, M, et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol, 1996;157;1261-1270.
    Pubmed
  4. Geremia, A, Biancheri, P, Allan, P, Corazza, GR, Di Sabatino, A. Innate and adaptive immunity in inflammatory bowel disease. Autoimmun Rev, 2014;13;3-10.
    Pubmed CrossRef
  5. Buisine, MP, Desreumaux, P, Debailleul, V, et al. Abnormalities in mucin gene expression in Crohn’s disease. Inflamm Bowel Dis, 1999;5;24-32.
    Pubmed CrossRef
  6. Kim, JM. Antimicrobial proteins in intestine and inflammatory bowel diseases. Intest Res, 2014;12;20-33.
    Pubmed KoreaMed CrossRef
  7. MacDonald, TT, Monteleone, I, Fantini, MC, Monteleone, G. Regulation of homeostasis and inflammation in the intestine. Gastroenterology, 2011;140;1768-1775.
    Pubmed CrossRef
  8. Romagnani, S. Lymphokine production by human T cells in disease states. Annu Rev Immunol, 1994;12;227-257.
    Pubmed CrossRef
  9. Siegmund, B, Zeitz, M. Innate and adaptive immunity in inflammatory bowel disease. World J Gastroenterol, 2011;17;3178-3183.
    Pubmed KoreaMed
  10. Kim, MJ, Lee, WY, Choe, YH. Expression of TIM-3, human β-defensin-2, and FOXP3 and correlation with disease activity in pediatric Crohn’s disease with infliximab therapy. Gut Liver, 2015;9;370-380.
    Pubmed CrossRef

Article

Editorial

Gut Liver 2015; 9(3): 263-264

Published online May 31, 2015 https://doi.org/10.5009/gnl15123

Copyright © Gut and Liver.

Cross-Regulation of Innate and Adaptive Immunity: A New Perspective for the Pathogenesis of Inflammatory Bowel Disease

Da Yeon Oh, and Seong-Joon Koh

Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul National University College of Medicine, Seoul, Korea

Correspondence to: Seong-Joon Koh, Division of Gastroenterology & Hepatology, Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 156-707, Korea, Tel: +82-2-870-2234, Fax: +82-2-870-3866, E-mail: jel1206@snu.ac.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    References

    1. Baumgart, DC, Sandborn, WJ. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet, 2007;369;1641-1657.
      Pubmed CrossRef
    2. Han, DS. Current status and prospects of intestinal microbiome studies. Intest Res, 2014;12;178-183.
      Pubmed KoreaMed CrossRef
    3. Fuss, IJ, Neurath, M, Boirivant, M, et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol, 1996;157;1261-1270.
      Pubmed
    4. Geremia, A, Biancheri, P, Allan, P, Corazza, GR, Di Sabatino, A. Innate and adaptive immunity in inflammatory bowel disease. Autoimmun Rev, 2014;13;3-10.
      Pubmed CrossRef
    5. Buisine, MP, Desreumaux, P, Debailleul, V, et al. Abnormalities in mucin gene expression in Crohn’s disease. Inflamm Bowel Dis, 1999;5;24-32.
      Pubmed CrossRef
    6. Kim, JM. Antimicrobial proteins in intestine and inflammatory bowel diseases. Intest Res, 2014;12;20-33.
      Pubmed KoreaMed CrossRef
    7. MacDonald, TT, Monteleone, I, Fantini, MC, Monteleone, G. Regulation of homeostasis and inflammation in the intestine. Gastroenterology, 2011;140;1768-1775.
      Pubmed CrossRef
    8. Romagnani, S. Lymphokine production by human T cells in disease states. Annu Rev Immunol, 1994;12;227-257.
      Pubmed CrossRef
    9. Siegmund, B, Zeitz, M. Innate and adaptive immunity in inflammatory bowel disease. World J Gastroenterol, 2011;17;3178-3183.
      Pubmed KoreaMed
    10. Kim, MJ, Lee, WY, Choe, YH. Expression of TIM-3, human β-defensin-2, and FOXP3 and correlation with disease activity in pediatric Crohn’s disease with infliximab therapy. Gut Liver, 2015;9;370-380.
      Pubmed CrossRef
    Gut and Liver

    Vol.17 No.6
    November, 2023

    pISSN 1976-2283
    eISSN 2005-1212

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