GNL Gut and Liver
  1. Haemin Lee, Sanggu Kim, Dohee Lee, Yeon Chae, Taesik Yun, Mhan-Pyo Yang, Byeong-Teck Kang, Soochong Kim, Hakhyun Kim. Case report: Fundic gland polyps caused by long-term omeprazole use in a Maltese dog. Front. Vet. Sci. 2023;10
    https://doi.org/10.3389/fvets.2023.1287335
  2. Wen-xin Wang, Rui-jie Li, Xiong-fei Li. Efficacy and Safety of Potassium-Competitive Acid Blockers vs Proton Pump Inhibitors for Peptic Ulcer Disease or Postprocedural Artificial Ulcers: A Systematic Review and Meta-analysis. Clin Transl Gastroenterol 2024;15:e1
    https://doi.org/10.14309/ctg.0000000000000754
  3. Su Hwan Kim, Ji Won Kim, Seong-Joon Koh, Sang Gyun Kim, Jeong Mo Bae, Jung Ho Kim, Jeong Hwan Park, Mee Soo Chang, Kee Don Choi, Hyoun Woo Kang, Byeong Gwan Kim, Kook Lae Lee. Tauroursodeoxycholic Acid Inhibits Nuclear Factor Kappa B Signaling in Gastric Epithelial Cells and Ameliorates Gastric Mucosal Damage in Mice. Korean J Gastroenterol 2022;79:161
    https://doi.org/10.4166/kjg.2022.003
  4. Ruilin Xie, Xueli Yan, Jing Yu, Kaixiang Shen, Mengyuan Zhang, Meng Li, Zhuting Lv, Yuchen Zhang, Zixi Zhang, Yi Lyu, Yilong Cheng, Dake Chu. pH-responsive bioadhesive with robust and stable wet adhesion for gastric ulcer healing. Biomaterials 2024;309:122599
    https://doi.org/10.1016/j.biomaterials.2024.122599
  5. Kimitoshi Kubo, Noriko Kimura, Mototsugu Kato. Potassium-competitive acid blocker-associated gastric mucosal lesions. Clin Endosc 2024;57:417
    https://doi.org/10.5946/ce.2023.279
  6. Diego Reyes-Placencia, Elisa Cantú-Germano, Gonzalo Latorre, Alberto Espino, Glòria Fernández-Esparrach, Leticia Moreira. Gastric Epithelial Polyps: Current Diagnosis, Management, and Endoscopic Frontiers. Cancers 2024;16:3771
    https://doi.org/10.3390/cancers16223771
  7. Manuel Cabrera Charleston, Daniela Guadalupe Oscura Paredes, Gabriela Alfaro Mendez, Jesus Manuel Cabrera Tello. Development of Gastric Polyps: 15 Years of Proton Pump Inhibitor Therapy . 2024
    https://doi.org/10.7759/cureus.60814
  8. Kadir GİŞİ. Gastric Polyps: Retrospective Analysis of a 10-Years Endoscopic Procedure. 2022;17:29
    https://doi.org/10.17517/ksutfd.1115823
  9. Larissa Zambom Côco, Rafaela Aires, Glaucimeire Rocha Carvalho, Eduarda de Souza Belisário, Michelle Khai Khun Yap, Fernanda Gobbi Amorim, Javier Conde-Aranda, Breno Valentim Nogueira, Elisardo Corral Vasquez, Thiago de Melo Costa Pereira, Bianca Prandi Campagnaro. Unravelling the Gastroprotective Potential of Kefir: Exploring Antioxidant Effects in Preventing Gastric Ulcers. Cells 2023;12:2799
    https://doi.org/10.3390/cells12242799
  10. Haiying Gong, Di Han, Zichen Luo, Qingping Zhu, Xiaolin Zhu, Sen Liu, Diping Chen. Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats. Phytomedicine 2023;118:154954
    https://doi.org/10.1016/j.phymed.2023.154954
  11. Zhenxing Li, Kunfeng Yan, Xiaorong Dai, Weiwei Rong. Study on the clinical efficacy of 14-day vonoprazan-based triple regimen in obese patients with Helicobacter pylori infection. Journal of Chemotherapy 2024:1
    https://doi.org/10.1080/1120009X.2024.2405353
  12. Gwang Ha Kim. Clinicians should be aware of proton pump inhibitor–related changes in the gastric mucosa. Clin Endosc 2024;57:51
    https://doi.org/10.5946/ce.2023.188
  13. Tomasz Kosmalski, Daria Kupczyk, Szymon Baumgart, Renata Paprocka, Renata Studzińska. A Review of Biologically Active Oxime Ethers. Molecules 2023;28:5041
    https://doi.org/10.3390/molecules28135041
  14. Yorinari Ochiai, Daisuke Kikuchi, Shu Hoteya, Chiara Ricci. Efficacy of Step‐Down Therapy Using Vonoprazan for Symptomatic Mild Reflux Esophagitis. Gastroenterology Research and Practice 2024;2024
    https://doi.org/10.1155/grp/5620034
  15. Lisu Li, Jincheng Jing, Shanshan Yang, Shumei Fang, Wenting Liu, Cong Wang, Ruixi Li, Ting Liu, Lin Zheng, Chang Yang. Bletilla striata Polysaccharide Nanoparticles Improved the Therapeutic Efficacy of Omeprazole on the Rat Gastric Ulcer Induced by Ethanol. Mol. Pharmaceutics 2023;20:1996
    https://doi.org/10.1021/acs.molpharmaceut.2c00922
  16. Haisheng Peng, Jiahe Wang, Jiayu Chen, Yanbo Peng, Xiaoxian Wang, Ying Chen, David L. Kaplan, Qun Wang. Challenges and opportunities in delivering oral peptides and proteins. Expert Opinion on Drug Delivery 2023;20:1349
    https://doi.org/10.1080/17425247.2023.2237408
  17. Jia Wei Chen, Gang Liu, Yan Fang Lin, Ting You, Li Jia Yao, Bao Shan Wang, Qing Hua Wang, Da Zhou Li, Wen Wang. Feasibility and efficacy of endoscopy with blue laser imaging for the detection and diagnosis of cardia polyps: A single‐center randomized controlled study. J of Digest Diseases 2024;25:191
    https://doi.org/10.1111/1751-2980.13267
  18. Masaya Iwamuro, Hidenori Shiraha, Hiroyuki Okada. Gastric polyps' regression after potassium‐competitive acid blocker cessation. J of Gen and Family Med 2022;23:358
    https://doi.org/10.1002/jgf2.552
  19. Satoshi Shinozaki, Hiroyuki Osawa, Yoshimasa Miura, Hiroaki Nomoto, Hirotsugu Sakamoto, Yoshikazu Hayashi, Tomonori Yano, Edward J. Despott, Hironori Yamamoto. Endoscopic findings and outcomes of gastric mucosal changes relating to potassium‐competitive acid blocker and proton pump inhibitor therapy. DEN Open 2025;5
    https://doi.org/10.1002/deo2.400
  20. Sun-Young Lee. Type A, Type B, and Non-atrophic Gastritis. Korean J Helicobacter Up Gastrointest Res 2023;23:108
    https://doi.org/10.7704/kjhugr.2023.0015
  21. Hiroko Suda, Koichi Sakurai, Sachi Eto, Satomi Fujie, Ayako Okuda, Takayuki Takeichi, Masayuki Urata, Tetsuya Murao, Kiwamu Hasuda, Masahiro Hirano, Yo Kato, Ken Haruma. Effects of Medication Period and Gastrin Levels on Endoscopic Gastric Mucosal Changes in Long-Term Proton Pump Inhibitor Users. Diagnostics 2024;14:2540
    https://doi.org/10.3390/diagnostics14222540
  22. Ryo Katsumata, Tomoari Kamada, Takahisa Murao, Aya Sunago, Mitsuhiko Suehiro, Yasumasa Monobe, Yoshiaki Iwasaki, Hirofumi Kawamoto, Hiroshi Nagai, Ken Haruma. A Case of Autoimmune Gastritis and Hepatitis with Enlarging Gastric Polyps after Reducing the Dose of Prednisolone. Case Rep Gastroenterol 2023;17:124
    https://doi.org/10.1159/000529151
  23. Akira Hokama, Mayumi Shiroma, Mami Tomiyama, Yuko Tasato, Maki Setake. Helicobacter pylori Eradication-Related Development of Multiple White and Flat Elevated Lesions in the Stomach. Chonnam Med J 2023;59:203
    https://doi.org/10.4068/cmj.2023.59.3.203
  24. Sergey M Kotelevets. Risks of anti-Helicobacter therapy and long-term therapy with antisecretory drugs. World J Gastroenterol 2025;31
    https://doi.org/10.3748/wjg.v31.i4.101933
  25. Masaya Iwamuro, Seiji Kawano, Motoyuki Otsuka. Drug-induced mucosal alterations observed during esophagogastroduodenoscopy. World J Gastroenterol 2024;30:2220
    https://doi.org/10.3748/wjg.v30.i16.2220
  26. Long Gao, Yuan Liu, Jiaying Liu, Jiali Li, Haotian Li, Yanyan Liu, Fang Meng, Xiaohong Du, Yufeng Gao, Jiabin Li, F. Xiao‐Feng Qin. Proton pump inhibitors stabilize the expression of PD‐L1 on cell membrane depending on the phosphorylation of GSK3β. Cancer Medicine 2024;13
    https://doi.org/10.1002/cam4.7083
  27. Hong-Xia Yuan, Liu-Jia Dong. Traditional Chinese medicine diagnosis and treatment strategies for gastroesophageal reflux disease. WCJD 2024;32:313
    https://doi.org/10.11569/wcjd.v32.i5.313
  28. Yoko Sato, Shinichi Ban, Yasumi Katayama, Takashi Mitsui. Unique membranous gastrin receptor expression of parietal cells and its distribution pattern in the gastric oxyntic mucosa and fundic gland polyps. Human Pathology 2022;125:23
    https://doi.org/10.1016/j.humpath.2022.04.001
  29. Shohei Igarashi, Norihiro Hanabata, Keisuke Furusawa, Shinya Suto, Miwa Satake, Koji Shimaya, Kosuke Kanazawa, Hiroshi Numao, Masaki Munakata, Hidekachi Kurotaki, Hirotake Sakuraba, Shigeaki Yoshida. Morphological change of foveolar‐type gastric adenocarcinoma after proton pump inhibitor discontinuation in a short time period: A case report. DEN Open 2024;4
    https://doi.org/10.1002/deo2.293
  30. Tai Zhang, Beihua Zhang, Jinkang Xu, Shunping Ren, Shaogang Huang, Zhaohong Shi, Shaoju Guo, Liqun Bian, Ping Wang, Fengyun Wang, Yidong Cai, Xudong Tang. Chinese herbal compound prescriptions combined with Chinese medicine powder based on traditional Chinese medicine syndrome differentiation for treatment of chronic atrophic gastritis with erosion: a multi-center, randomized, positive-controlled clinical trial. Chin Med 2022;17
    https://doi.org/10.1186/s13020-022-00692-7
  31. Xueying Wang, Xuejiao Wang, Mingyuan Wen, Xiaolong Li. Bibliometric analysis of literature on prevention and treatment of gastric ulcer with natural medicines. Journal of Future Foods 2023;3:225
    https://doi.org/10.1016/j.jfutfo.2023.02.004
  32. Hiroaki Kaneko, Hiroki Sato, Yuichi Suzuki, Aya Ikeda, Hirofumi Kuwashima, Ryosuke Ikeda, Takeshi Sato, Kuniyasu Irie, Soichiro Sue, Shin Maeda. A Novel Characteristic Gastric Mucus Named “Web-like Mucus” Potentially Induced by Vonoprazan. JCM 2024;13:4070
    https://doi.org/10.3390/jcm13144070
  33. Zhiwei Hu, Jimin Wu, Zhonggao Wang, Xinghua Bai, Yu Lan, Kefang Lai, Abudureyimu Kelimu, Feng Ji, Zhenling Ji, Diyu Huang, Zhiwei Hu, Xiaohua Hou, Jianyu Hao, Zhining Fan, Xiaoping Chen, Dong Chen, Shengliang Chen, Jinrang Li, Junxiang Li, Lan Li, Peng Li, Zhigang Li, Lin Lin, Bianying Liu, Dian-gang Liu, Yiping Lu, Bin Lü, Qiuping Lü, Ming Qiu, Zhongmin Qiu, Huajao Shen, Jun Tai, Yanping Tang, Wen Tian, Zhonghao Wang, Bangmao Wang, Jian-an Wang, Ju Wang, Qi Wang, Songling Wang, Wen Wang, Zhifei Wang, Wei Wei, Zhiwei Wu, Wei Wu, YanQiao Wu, Yu Wu, Jixiang Wu, Yinglian Xiao, Wen Xu, Xiwei Xu, Fuquan Yang, HuiQi Yang, Yunsheng Yang, Qiyuan Yao, Chunzhao Yu, Peng Zhang, Xiaolan Zhang, Taicheng Zhou, Duowu Zou. Chinese consensus on multidisciplinary diagnosis and treatment of gastroesophageal reflux disease 2022. Gastroenterology & Endoscopy 2023;1:33
    https://doi.org/10.1016/j.gande.2023.01.001
  34. Sara Massironi, Camilla Gallo, Edith Lahner, Valentina Sciola, Federica Cavalcoli, Marco Vincenzo Lenti, Alessandra Zilli, Ludovica Dottori, Gaia De Rossi, Emanuela Miceli, Bruno Annibale, Maurizio Vecchi, Paolo Cantù, Antonio Di Sabatino, Pietro Invernizzi, Silvio Danese. Occurrence and characteristics of endoscopic gastric polyps in patients with autoimmune gastritis (AGAPE study): A multicentric cross-sectional study. Digestive and Liver Disease 2025;57:198
    https://doi.org/10.1016/j.dld.2024.07.024
  35. . .
    https://doi.org/
  36. Jong Hyeon Jeong, Sun-Young Lee, Hye Seung Han. Gastric Corpus Hypertrophy with a Bleeding Hyperplastic Polyp in a Helicobacter pylori-naive Subject after Long-term Proton Pump Inhibitor Use. Korean J Helicobacter Up Gastrointest Res 2022;22:63
    https://doi.org/10.7704/kjhugr.2021.0062
  37. 重杰 李. Research Progress on Risk Factors Related to Gastric Fundus Glandular Polyps. ACM 2023;13:20008
    https://doi.org/10.12677/ACM.2023.13122818
  38. C. Van Der Pluijm, P. Deprez, L. Libbrecht, A. Jouret-Mourin, H. Dano. Diagnostic Pitfall of Gastric Signet-Ring Cells: How to Diagnose a Benign Signet-Ring Cell From a Malignant One. Int J Surg Pathol 2024;32:1477
    https://doi.org/10.1177/10668969241235317
  39. Gwang Ha Kim, Hang Lak Lee, Moon Kyung Joo, Hong Jun Park, Sung Woo Jung, Ok-Jae Lee, Hyungkil Kim, Hoon Jai Chun, Soo Teik Lee, Ji Won Kim, Han Ho Jeon, Il-Kwun Chung, Hyun-Soo Kim, Dong Ho Lee, Kyoung-Oh Kim, Yun Jeong Lim, Seun-Ja Park, Soo-Jeong Cho, Byung-Wook Kim, Kwang Hyun Ko, Seong Woo Jeon, Jae Gyu Kim, In-Kyung Sung, Tae Nyeun Kim, Jae Kyu Sung, Jong-Jae Park. Efficacy and Safety of Rebamipide versus Its New Formulation, AD-203, in Patients with Erosive Gastritis: A Randomized, Double-Blind, Active Control, Noninferiority, Multicenter, Phase 3 Study. Gut and Liver 2021;15:841
    https://doi.org/10.5009/gnl20338
  40. Chihiro Sato, Kazuya Takahashi, Hiroki Sato, Takumi Naruse, Nao Nakajima, Masafumi Takatsuna, Ken-ichi Mizuno, Satoru Hashimoto, Manabu Takeuchi, Junji Yokoyama, Masaaki Kobayashi, Shuji Terai. Endoscopic Findings and Treatment of Gastric Neoplasms in Familial Adenomatous Polyposis. J Gastric Cancer 2022;22:381
    https://doi.org/10.5230/jgc.2022.22.e30
  41. Shupeng Zou, Mengling Ouyang, Qian Cheng, Xuan Shi, Minghui Sun. Acid‐suppressive drugs: A systematic review and network meta‐analysis of their nocturnal acid‐inhibitory effect. Pharmacotherapy 2024;44:171
    https://doi.org/10.1002/phar.2899
  42. Yutong Jiang, Rongrong Zhang, Yuxuan Fang, Ruixia Zhao, Yu Fu, Pingping Ren, Qingqing Zhan, Mingyi Shao. P-CAB versus PPI in the eradication of Helicobacter pylori: a systematic review and network meta-analysis. Therap Adv Gastroenterol 2024;17
    https://doi.org/10.1177/17562848241241223
  43. Jonathan A. Salazar, Jeffrey D. Goldsmith, Lissette Jimenez, Victor L. Fox, Christopher P. Duggan, Alexandra N. Carey. Gastric Foveolar Hyperplastic Polyps in 2 Children With Short Bowel Syndrome on Long-Term Teduglutide. 2023;4:e389
    https://doi.org/10.1097/PG9.0000000000000389
  44. Yu-Ru Chen, Hsiu-Man Lien, Fuu-Jen Tsai, Jiunn-Wang Liao, Yng-Tay Chen. The Gastroprotective Effects of Anisomeles indica against Ethanol-Induced Gastric Ulcer through the Induction of IκB-α and the Inhibition of NF-κB Expression. Nutrients 2024;16:2297
    https://doi.org/10.3390/nu16142297
  45. Da-Hai Hu, Wan-Ching Wong, Jia-Xin Zhou, Ji Luo, Song-Wang Cai, Hong Zhou, Hui Tang, Jiang Pi. The Correlation between the Use of the Proton Pump Inhibitor and the Clinical Efficacy of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer. Journal of Oncology 2022;2022:1
    https://doi.org/10.1155/2022/1001796
  46. Natalia M. Khomeriki, Sergey G. Khomeriki. Is an optimization of the use of proton pump inhibitors feasible in the real world medical practice?. Almanac of Clinical Medicine 2023;50:357
    https://doi.org/10.18786/2072-0505-2022-50-051
  47. I. V. Koshurba, F. V. Hladkykh, M. O. Chyzh. Modern approaches to the treatment of peptic ulcer disease and prospects for the use of biological therapy. Modern Medical Technology 2023:58
    https://doi.org/10.34287/MMT.2(57).2023.10
  48. Shuting Wen, Xiying Zhao, Xiaofeng Lin, Zhaoli Fu, Shumin Qin, Qimou Pan, Fengbin Liu, Wenfang He, Tianwen Liu. Acupoint catgut embedding advantage in treating gastro-oesophageal reflux disease (ACE-GERD): study protocol for a randomised controlled trial. BMJ Open 2024;14:e081059
    https://doi.org/10.1136/bmjopen-2023-081059
  49. Akira Kanamori, Keiichi Tominaga, Hironori Masuyama, Mutsumi Ishikawa, Satoshi Masuyama, Masayuki Kondo, Mimari Kanazawa, Takanao Tanaka, Masamichi Yamaura, Keiichiro Abe, Shoko Watanabe, Akira Yamamiya, Yoko Abe, Kenichi Goda, Atsushi Irisawa. Size reduction of gastric fundic gland polyposis by de‐escalation of acid‐suppressive therapy. DEN Open 2023;3
    https://doi.org/10.1002/deo2.135
  50. Cheol Min Shin. Acid Suppressive Drugs. Korean J Helicobacter Up Gastrointest Res 2022;22:119
    https://doi.org/10.7704/kjhugr.2022.0016
  51. Xin Luo, Hui Li, Li He. Correlation analysis of endoscopic manifestations and eradication effect of Helicobacter pylori. Front. Med. 2023;10
    https://doi.org/10.3389/fmed.2023.1259728
  52. Malek Michael Bouhairie, Racha Elseblani, Remi Lakis, Mahmoud Hallal. Gastric Polyps in Long-Term Proton Pump Inhibitor Use: Identification of Risks and Characteristics. 2024
    https://doi.org/10.7759/cureus.62365
  53. Rino Hasegawa, Kenshi Yao, Takao Kanemitsu, Hisatomi Arima, Takayuki Hirase, Yuuya Hiratsuka, Kazuhiro Takeda, Kentaro Imamura, Kensei Ohtsu, Yoichiro Ono, Masaki Miyaoka, Takashi Hisabe, Toshiharu Ueki, Hiroshi Tanabe, Atsuko Ohta, Satoshi Nimura. Association between occurrence of multiple white and flat elevated gastric lesions and oral proton pump inhibitor intake. Clin Endosc 2024;57:65
    https://doi.org/10.5946/ce.2022.257
  54. Zeyi Zheng, Ziyu Lu, Yani Song. Long-term proton pump inhibitors use and its association with premalignant gastric lesions: a systematic review and meta-analysis. Front. Pharmacol. 2023;14
    https://doi.org/10.3389/fphar.2023.1244400
  55. Yinglin Guo, Yufan Wu, Tairun Huang, Dehao Huang, Quanfu Zeng, Zhuxian Wang, Yi Hu, Peiyi Liang, Hongkai Chen, Zeying Zheng, Tao Liang, Dan Zhai, Cuiping Jiang, Li Liu, Hongxia Zhu, Qiang Liu. Licorice flavonoid ameliorates ethanol-induced gastric ulcer in rats by suppressing apoptosis via PI3K/AKT signaling pathway. Journal of Ethnopharmacology 2024;325:117739
    https://doi.org/10.1016/j.jep.2024.117739
  56. Feidi Chen, Raul S Gonzalez. Evaluation of enterochromaffin-like cell hyperplasia can help categorize patients with Helicobacter-negative atrophic gastritis. 2024
    https://doi.org/10.1093/ajcp/aqae159
  57. Sara Massironi, Alessandra Elvevi, Camilla Gallo, Alice Laffusa, Anna Tortorella, Pietro Invernizzi. Exploring the spectrum of incidental gastric polyps in autoimmune gastritis. Digestive and Liver Disease 2023;55:1201
    https://doi.org/10.1016/j.dld.2023.02.008
  58. Masaya Iwamuro, Yoshiyasu Kono, Takehiro Tanaka, Seiji Kawano, Nobumasa Ikeda. Vonoprazan-Associated Mucosal Redness: A Report of Two Cases. 2024
    https://doi.org/10.7759/cureus.71325
  59. Cheng Shen, Changping Li, Muhan Lv, Xiaosong Dai, Caiping Gao, Liangping Li, Qin Zhang, Wen Pan, Chao Liu, Sijing Han, Yang Zhang, Shunbin Ding, Hong Deng, Yong Yao, Jianyu Xu, Mingyong Wei, Haiyan Shi, Peijie Yuan, Xiaoyan Yang, Yi Jian, Jing Shan, Yan Liu, Zonghua Chen, Xuejie Deng, Fei Liu, Lijuan Deng, Xianfei Zhong, Hong Li, Shaoya He, Li Chen, Gang Liu, Hairong Xu, Yuquan Zhong, Hua Shi, Jiangang Ren. The prospective multiple-centre randomized controlled clinical study of high-dose amoxicillin-proton pump inhibitor dual therapy for H. pylori infection in Sichuan areas . Annals of Medicine 2022;54:426
    https://doi.org/10.1080/07853890.2022.2031269
  60. Eun Jeong Gong, Chang Seok Bang. Whitish gastric mucosa on upper gastrointestinal endoscopy. Clin Endosc 2024;57:277
    https://doi.org/10.5946/ce.2024.016
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