- Baohua Chen, Kay Perry, Rongsheng Jin. Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies. Front. Immunol. 2022;13

- Chetana Vaishnavi, Meenakshi Singh, Safrun Mahmood, Rakesh Kochhar. Prevalence and molecular types of Clostridium difficile isolates from faecal specimens of patients in a tertiary care centre. 2015;64:1297

- Meng Wang, Zifeng Deng, Yanmei Li, Yi Ma, Jufang Wang. Design and characterization of a novel lytic protein against Clostridium difficile. Appl Microbiol Biotechnol 2022;106:4511

- D. N. Gerding, D. W. Hecht, T. Louie, C. E. Nord, G. H. Talbot, O. A. Cornely, M. Buitrago, E. Best, S. Sambol, J. R. Osmolski, H. Kracker, H. H. Locher, P. Charef, M. Wilcox. Susceptibility ofClostridium difficileisolates from a Phase 2 clinical trial of cadazolid and vancomycin inC. difficileinfection. J. Antimicrob. Chemother. 2016;71:213

- S. Gemein, J. Gebel, B. Christiansen, H. Martiny, L. Vossebein, F.H.H. Brill, M. Decius, M. Eggers, T. Koburger-Janssen, M. Meckel, S. Werner, B. Hunsinger, T. Selhorst, G. Kampf, M. Exner. Interlaboratory reproducibility of a test method following 4-field test methodology to evaluate the susceptibility of Clostridium difficile spores. Journal of Hospital Infection 2019;103:78

- Mengjun Tang, Chunhua Wang, Ying Xia, Jian Tang, Jiao Wang, Liang Shen. Clostridioides difficile infection in inflammatory bowel disease: a clinical review. Expert Review of Anti-infective Therapy 2024;22:297

- James L. A. Webb, Jr. The Guts of the Matter. 2024.

- Víctor H. Pérez-Luna, Orfil González-Reynoso. Encapsulation of Biological Agents in Hydrogels for Therapeutic Applications. Gels 2018;4:61

- H.B. Ghoddusi, L.V. Thomas. Probiotic Dairy Products. 2018.

- Qingqing Xiong, Jing Zhao, Chenying Tian, Wan Ma, Linfeng Miao, Li Liang, Kang Zhang, Huahua Du. Regulation of a High-Iron Diet on Lipid Metabolism and Gut Microbiota in Mice. Animals 2022;12:2063

- Zhao Hai, Lei Peng Zhen, Ma Juan, Yang Fan, Cang Jin Rong, Liang Jing Yao, Zhang Li Xia. Extraintestinal Clostridioides difficile infection. IDCases 2020;22:e00921

- Huawei Gu, Kan Shi, Zhengping Liao, Haonan Qi, Shuyi Chen, Haiying Wang, Shan Li, Yi Ma, Jufang Wang. Time-resolved transcriptome analysis of Clostridium difficile R20291 response to cysteine. Microbiological Research 2018;215:114

- Xinyue Zhang, Jie Li, Chao Chen, Ya-Jun Liu, Qiu Cui, Wei Hong, Zhenghong Chen, Yingang Feng, Guzhen Cui. Molecular Basis of TcdR-Dependent Promoter Activity for Toxin Production by Clostridioides difficile Studied by a Heterologous Reporter System. Toxins 2023;15:306

- Hiroshi Sekiya, Eiji Tamai, Jurina Kawasaki, Kaho Murakami, Shigehiro Kamitori. Structural and biochemical characterizations of the novel autolysin Acd24020 from Clostridioides difficile and its full‐function catalytic domain as a lytic enzyme. Molecular Microbiology 2021;115:684

- Jeffrey Vietri, Martine C. Maculaitis, Joseph C. Cappelleri, Holly Yu, Lewis Kopenhafer, Kathleen Beusterien. Preferences for a Clostridioides difficile vaccine among adults in the United States. Vaccine 2024;42:126261

- Mwanaisha Seugendo, Aldofine Hokororo, Rogatus Kabyemera, Delfina R. Msanga, Mariam M. Mirambo, Vitus Silago, Uwe Groß, Stephen E. Mshana. High Clostridium difficile Infection among HIV-Infected Children with Diarrhea in a Tertiary Hospital in Mwanza, Tanzania. International Journal of Pediatrics 2020;2020:1

- Yuya Okada, Norihito Kaku, Kosuke Kosai, Naoki Uno, Yoshitomo Morinaga, Hiroo Hasegawa, Katsunori Yanagihara. Molecular epidemiology of Clostridioides difficile and risk factors for the detection of toxin gene-positive strains. Journal of Infection and Chemotherapy 2019;25:262

- Areej A Samman, Mona Alfares, Raghad A Bajabur , Roaa O Alnefaie, Lama S Alwadai , Weaam W Murad, Bayan M Dahal. Prevalence and Risk Factors of Clostridium difficile Infection Among Patients Hospitalized for a Flare of Inflammatory Bowel Disease in King Abdulaziz University Hospital. 2023

- Yu Mi Lee, Kyu Chan Huh, Soon Man Yoon, Byung Ik Jang, Jeong Eun Shin, Hoon Sup Koo, Yunho Jung, Sae Hee Kim, Hee Seok Moon, Seung Woo Lee. Incidence and Clinical Outcomes of Clostridium difficile Infection after Treatment with Tuberculosis Medication. Gut Liver 2016;10:250

- Fei Wang, Zetian Wang, Jianguo Tang. The interactions of Candida albicans with gut bacteria: a new strategy to prevent and treat invasive intestinal candidiasis. Gut Pathog 2023;15

- Evelyn Balsells, Ting Shi, Callum Leese, Iona Lyell, John Burrows, Camilla Wiuff, Harry Campbell, Moe H Kyaw, Harish Nair. Global burden of Clostridium difficile infections: a systematic review and meta-analysis. 2019;9

- Jana Makroczyová, Ján Jamroškovič, Eva Krascsenitsová, Nad'a Labajová, Imrich Barák. Oscillating behavior of Clostridium difficile Min proteins in Bacillus subtilis. MicrobiologyOpen 2016;5:387

- Rajesh Venkataraman, Umesh Yadav, Ravi Kurikempannadoddi Shivalingegowda, Yogendra Shrestha. Vaccination strategies to combat nosocomial infections. Vacunas 2023;24:60

- Desiderio Favarato, Luiz Alberto Benvenuti. Caso 1/2020 - Mulher de 55 Anos com Insuficiência Cardíaca após Internação por Diagnóstico Presumido de Infarto do Miocárdio e Insuficiência da Valva Mitral com Rotura de Corda Tendínea. 2020;114:47

- Angela María Barbero, Rodrigo Emanuel Hernández Del Pino, Federico Fuentes, Paula Barrionuevo, Virginia Pasquinelli. Platelets promote human macrophages-mediated macropinocytosis of Clostridioides difficile. Front. Cell. Infect. Microbiol. 2024;13

- Lyudmila Boyanova, Rumyana Markovska, Petyo Hadzhiyski, Daniel Yordanov, Penka Yaneva, Ivan Mitov. Recurrent Clostridioides (Clostridium) difficile infection in a patient suffering from inflammatory bowel disease and benefits of resistotyping. Diagnostic Microbiology and Infectious Disease 2019;94:334

- Rowena Almeida, Teklu Gerbaba, Elaine O. Petrof. Recurrent Clostridium difficile infection and the microbiome. J Gastroenterol 2016;51:1

- Tali Friedman-Korn, Dan Meir Livovsky, Nitsan Maharshak, Nathaniel Aviv Cohen, Kalman Paz, Ariella Bar-Gil Shitrit, Eran Goldin, Benjamin Koslowsky. Fecal Transplantation for Treatment of Clostridium Difficile Infection in Elderly and Debilitated Patients. Dig Dis Sci 2018;63:198

- George J. Li, Justin Trac, Shahid Husain, Olusegun Famure, Yanhong Li, S. Joseph Kim. Incidence, Risk Factors, and Outcomes of Clostridium difficile Infections in Kidney Transplant Recipients. 2018;102:1576

- Hsiao-Ting Yang, Jenn-Wei Chen, Jagat Rathod, Yu-Zhen Jiang, Pei-Jane Tsai, Yuan-Pin Hung, Wen-Chien Ko, Daniel Paredes-Sabja, I-Hsiu Huang. Lauric Acid Is an Inhibitor of Clostridium difficile Growth in Vitro and Reduces Inflammation in a Mouse Infection Model. Front. Microbiol. 2018;8

- Meenakshi Singh, Chetana Vaishnavi, Safrun Mahmood, Rakesh Kochhar. Surveillance for Antibiotic Resistance in <i>Clostridium difficile</i> Strains Isolated from Patients in a Tertiary Care Center. AiM 2015;05:336

- . Imaging in Gastroenterology. 2015.

- Hiroyuki Kunishima, Kaoru Ito, Thomas Laurent, Machiko Abe. Healthcare burden of recurrent Clostridioides difficile infection in Japan: A retrospective database study. Journal of Infection and Chemotherapy 2018;24:892

- Mohamed Ismail, Ritik Goyal, Menna-Allah A Elaskandrany, Michael Bebawy, Sahiba Singh, Claire Ruane, Weizheng Wang. Atypical Clostridium difficile Infection in a Pregnant Patient: A Case Study on Non-Diarrheal Presentation and Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Complication. 2024

- Sherin Justin, Beena Antony. POLYMERASE CHAIN REACTION FOR THE DETECTION OF TOXIN A ( TCD A ) AND TOXIN B ( TCD B ) GENES OF CLOSTRIDIUM DIFFICILE ISOLATED FROM DIARRHOEAL CASES AND ANALYSIS OF THE CLINICAL SPECTRUM. jemds 2015;4:4938

- Jae Yoon Na, Jong Mo Park, Kyung Suk Lee, Jung Oak Kang, Sung Hee Oh, Yong Joo Kim. Clinical Characteristics of SymptomaticClostridium difficileInfection in Children: Conditions as Infection Risks and Whether Probiotics Is Effective. Pediatr Gastroenterol Hepatol Nutr 2014;17:232

- Eun Mi Song, Arum Choi, Sukil Kim, Sung Hoon Jung. The Prevalence and Risk Factors of Clostridioides difficile Infection in Inflammatory Bowel Disease: 10-Year South Korean Experience Based on the National Database. J Korean Med Sci 2023;38

- A. Romero-Rodríguez, S. Troncoso-Cotal, E. Guerrero-Araya, D. Paredes-Sabja, Craig D. Ellermeier. The Clostridioides difficile Cysteine-Rich Exosporium Morphogenetic Protein, CdeC, Exhibits Self-Assembly Properties That Lead to Organized Inclusion Bodies in Escherichia coli. mSphere 2020;5

- Sophia Julia Häfner. Big browser is watching you. Microbes and Infection 2018;20:271

- Erika J. Goldberg, Sumit Bhalodia, Sherin Jacob, Hatil Patel, Ken V. Trinh, Blessy Varghese, Jungmo Yang, Sean R. Young, Robert B. Raffa. Clostridium difficileinfection: A brief update on emerging therapies. 2015;72:1007

- Hyuk Yoon, Hyun Ik Shim, Mijin Seol, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee. Factors Related to Outcomes of Fecal Microbiota Transplantation in Patients with Clostridioides difficile Infection. Gut and Liver 2021;15:61

- Ying Liu, Yaxi Wang, Fei Wei, Lihong Chai, Hongyuan Wang. Gut microbiota-bile acid crosstalk contributes to intestinal damage after nitrate exposure in Bufo gargarizans tadpoles. Science of The Total Environment 2024;943:173795

- Eric Bordeleau, Vincent Burrus. Cyclic-di-GMP signaling in the Gram-positive pathogen Clostridium difficile. Curr Genet 2015;61:497

- Jiyoun Song, Bevin Cohen, Philip Zachariah, Jianfang Liu, Elaine L. Larson. Temporal change of risk factors in hospital-acquired Clostridioides difficile infection using time-trend analysis. Infect. Control Hosp. Epidemiol. 2020;41:1048

- Hiroshi Sekiya, Hina Yamaji, Ayumi Yoshida, Risa Matsunami, Shigehiro Kamitori, Eiji Tamai. Biochemical Characterizations of the Putative Endolysin Ecd09610 Catalytic Domain from Clostridioides difficile. Antibiotics 2022;11:1131

- Anastasia S. Ivanova, Olga A. Obukhova. Nutritional support as a part of complex therapy for clostridial infection. Clinical nutrition and metabolism 2023;4:165

- Zheng-Ben Wu, Kai-Feng Meng, Li-Guo Ding, Sha Wu, Guang-Kun Han, Xue Zhai, Ru-Han Sun, Yong-yao Yu, Wei Ji, Zhen Xu. Dynamic Interaction Between Mucosal Immunity and Microbiota Drives Nose and Pharynx Homeostasis of Common Carp (Cyprinus carpio) After SVCV Infection. Front. Immunol. 2021;12

- Aaron Hunt, Emily Drwiega, Yifan Wang, Larry Danziger. A review of fecal microbiota, live-jslm for the prevention of recurrent Clostridioides difficile infection. 2024;81:e402

- Amgad Zaky, Sarah J. Glastras, May Y. W. Wong, Carol A. Pollock, Sonia Saad. The Role of the Gut Microbiome in Diabetes and Obesity-Related Kidney Disease. IJMS 2021;22:9641

- Elena A. Usacheva, Jian-P. Jin, Lance R. Peterson. Host response to Clostridium difficile infection: Diagnostics and detection. Journal of Global Antimicrobial Resistance 2016;7:93

- Katarzyna Pacyga, Agnieszka Razim, Gayane Martirosian, Małgorzata Aptekorz, Andrzej Szuba, Andrzej Gamian, Andrzej Myc, Sabina Górska. The Bioinformatic and In Vitro Studies of Clostridioides Difficile Aminopeptidase M24 Revealed the Immunoreactive KKGIK Peptide. Cells 2020;9:1146

- Daniel Curcio, Alejandro Cané, Francisco Andrés Fernández, Jorge Correa.
Clostridium difficile-associated Diarrhea in Developing Countries: A Systematic Review and Meta-Analysis. Infect Dis Ther 2019;8:87

- Ashish K. Sharma, Jenie Phue, Emir Khatipov, Nimish Dalal, Eric D. Anderson, Joseph Shiloach. Effect of restricted dissolved oxygen on expression of Clostridium difficile toxin A subunit from E. coli. Sci Rep 2020;10

- Frederick J. Angulo, Canna Ghia, Mark A. Fletcher, Egemen Ozbilgili, Graciela del Carmen Morales. The burden of Clostridioides difficile infections in South-East Asia and the Western Pacific: A narrative review. Anaerobe 2024;86:102821

- Hanna Dziewiecka, Harpal S. Buttar, Anna Kasperska, Joanna Ostapiuk–Karolczuk, Małgorzata Domagalska, Justyna Cichoń, Anna Skarpańska-Stejnborn. Physical activity induced alterations of gut microbiota in humans: a systematic review. BMC Sports Sci Med Rehabil 2022;14

- Leilei Li, Ya'nan Yang, Ying Cao, Jiaguo Zhan, Yan Wu, Chongming Wu. Perspective on the Modern Interpretation of the Property Theory of Mild-natured and Sweet-flavored Traditional Chinese Medicine via Gut Microbiota Modulation. Integr Med Nephrol Androl 2023;10

- Jing-Hui Tian, Gregory Glenn, David Flyer, Bin Zhou, Ye Liu, Eddie Sullivan, Hua Wu, James F. Cummings, Larry Elllingsworth, Gale Smith. Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models. Vaccine 2017;35:4079

- Daniela Zilio Larentis, Regis Goulart Rosa, Rodrigo Pires dos Santos, Luciano Zubaran Goldani. Outcomes and Risk Factors Associated withClostridium difficileDiarrhea in Hospitalized Adult Patients. Gastroenterology Research and Practice 2015;2015:1

- Alba Romero-Rodríguez, Daniel Paredes-Sabja. Molecular Medical Microbiology. 2015.

- Dominika Lachowicz, Hanna Pituch, Piotr Obuch-Woszczatyński. Antimicrobial susceptibility patterns of Clostridium difficile strains belonging to different polymerase chain reaction ribotypes isolated in Poland in 2012. Anaerobe 2015;31:37

- Steffen Brauns, Isabel Marquardt, Cosima Thon, Sarah Frentzel, Josefine Jakob, Jacqueline Färber, Lars Philipsen, Lothar Jänsch, Alexander Link, Dunja Bruder. Mucosal-associated invariant T cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity. 2023;35:543

- Shinsmon Jose, David Terrero-Salcedo, Rajat Madan. Molecular Medical Microbiology. 2023.

- M. Rätsep, S. Kõljalg, E. Sepp, I. Smidt, K. Truusalu, E. Songisepp, J. Stsepetova, P. Naaber, R.H. Mikelsaar, M. Mikelsaar. A combination of the probiotic and prebiotic product can prevent the germination of Clostridium difficile spores and infection. Anaerobe 2017;47:94

- Alba Romero-Rodríguez, Beatriz Ruiz-Villafán, Claudia Fabiola Martínez-de la Peña, Sergio Sánchez. Targeting the Impossible: A Review of New Strategies against Endospores. Antibiotics 2023;12:248

- Margarita Camorlinga, Michelle Sanchez-Rojas, Javier Torres, Mariana Romo-Castillo. Phenotypic Characterization of Non-toxigenic Clostridioides difficile Strains Isolated From Patients in Mexico. Front. Microbiol. 2019;10

- Abhay Thandavaram, Aneeta Channar, Ansh Purohit, Bijay Shrestha, Deepkumar Patel, Hriday Shah, Kerollos Hanna, Harkirat Kaur, Mohammad S Alazzeh, Lubna Mohammed. The Efficacy of Bezlotoxumab in the Prevention of Recurrent Clostridium difficile: A Systematic Review. 2022

- V. Beran, E. J. Kuijper, C. Harmanus, I. M. Sanders, S. M. van Dorp, C. W. Knetsch, J. Janeckova, A. Seidelova, L. Barekova, J. Tvrdik, D. Chmelar, I. Ciznar. Molecular typing and antimicrobial susceptibility testing to six antimicrobials of Clostridium difficile isolates from three Czech hospitals in Eastern Bohemia in 2011–2012. Folia Microbiol 2017;62:445

- Arijit Nath, Rahul Bhattacharjee, Aditya Nandi, Adrija Sinha, Sulagna Kar, Nikita Manoharan, Shirsajit Mitra, Abhik Mojumdar, Pritam Kumar Panda, Swadheena Patro, Ateet Dutt, Rajeev Ahuja, Suresh K. Verma, Mrutyunjay Suar. Phage delivered CRISPR-Cas system to combat multidrug-resistant pathogens in gut microbiome. Biomedicine & Pharmacotherapy 2022;151:113122

- Tetsuo Yamaguchi, Hiroe Konishi, Kotaro Aoki, Yoshikazu Ishii, Koji Chono, Kazuhiro Tateda. The gut microbiome diversity of Clostridioides difficile-inoculated mice treated with vancomycin and fidaxomicin. Journal of Infection and Chemotherapy 2020;26:483

- Christopher Troeger, Brigette F Blacker, Ibrahim A Khalil, Puja C Rao, Shujin Cao, Stephanie RM Zimsen, Samuel B Albertson, Jeffery D Stanaway, Aniruddha Deshpande, Zegeye Abebe, Nelson Alvis-Guzman, Azmeraw T Amare, Solomon W Asgedom, Zelalem Alamrew Anteneh, Carl Abelardo T Antonio, Olatunde Aremu, Ephrem Tsegay Asfaw, Tesfay Mehari Atey, Suleman Atique, Euripide Frinel G Arthur Avokpaho, Ashish Awasthi, Henok Tadesse Ayele, Aleksandra Barac, Mauricio L Barreto, Quique Bassat, Saba Abraham Belay, Isabela M Bensenor, Zulfiqar A Bhutta, Ali Bijani, Hailemichael Bizuneh, Carlos A Castañeda-Orjuela, Abel Fekadu Dadi, Lalit Dandona, Rakhi Dandona, Huyen Phuc Do, Manisha Dubey, Eleonora Dubljanin, Dumessa Edessa, Aman Yesuf Endries, Babak Eshrati, Tamer Farag, Garumma Tolu Feyissa, Kyle J Foreman, Mohammad H Forouzanfar, Nancy Fullman, Peter W Gething, Melkamu Dedefo Gishu, William W Godwin, Harish Chander Gugnani, Rahul Gupta, Gessessew Bugssa Hailu, Hamid Yimam Hassen, Desalegn Tsegaw Hibstu, Olayinka S Ilesanmi, Jost B Jonas, Amaha Kahsay, Gagandeep Kang, Amir Kasaeian, Yousef Saleh Khader, Ibrahim A Khalil, Ejaz Ahmad Khan, Muhammad Ali Khan, Young-Ho Khang, Niranjan Kissoon, Sonali Kochhar, Karen L Kotloff, Ai Koyanagi, G Anil Kumar, Hassan Magdy Abd El Razek, Reza Malekzadeh, Deborah Carvalho Malta, Suresh Mehata, Walter Mendoza, Desalegn Tadese Mengistu, Bereket Gebremichael Menota, Haftay Berhane Mezgebe, Fitsum Weldegebreal Mlashu, Srinivas Murthy, Gurudatta A Naik, Cuong Tat Nguyen, Trang Huyen Nguyen, Dina Nur Anggraini Ningrum, Felix Akpojene Ogbo, Andrew Toyin Olagunju, Deepak Paudel, James A Platts-Mills, Mostafa Qorbani, Anwar Rafay, Rajesh Kumar Rai, Saleem M Rana, Chhabi Lal Ranabhat, Davide Rasella, Sarah E Ray, Cesar Reis, Andre MN Renzaho, Mohammad Sadegh Rezai, George Mugambage Ruhago, Saeid Safiri, Joshua A Salomon, Juan Ramon Sanabria, Benn Sartorius, Monika Sawhney, Sadaf G Sepanlou, Mika Shigematsu, Mekonnen Sisay, Ranjani Somayaji, Chandrashekhar T Sreeramareddy, Bryan L Sykes, Getachew Redae Taffere, Roman Topor-Madry, Bach Xuan Tran, Kald Beshir Tuem, Kingsley Nnanna Ukwaja, Stein Emil Vollset, Judd L Walson, Marcia R Weaver, Kidu Gidey Weldegwergs, Andrea Werdecker, Abdulhalik Workicho, Muluken Yenesew, Biruck Desalegn Yirsaw, Naohiro Yonemoto, Maysaa El Sayed Zaki, Theo Vos, Stephen S Lim, Mohsen Naghavi, Christopher JL Murray, Ali H Mokdad, Simon I Hay, Robert C Reiner. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Infectious Diseases 2018;18:1211

- Brandon M Shore, Kimberly N Weaver, Jessica R Allegretti, Hans H Herfarth, Edward L Barnes. Prevalence of Clostridioides difficile Infection After Ileal Pouch-anal Anastomosis in Patients With Chronic Antibiotic-dependent Pouchitis and Crohn’s-like Disease of the Pouch. 2023;29:932

- Yuan Yuan, Guosheng Zhao, Hongwei Ji, Bin Peng, Zhiguo Huang, Wei Jin, Xiaoqiang Chen, Haitao Guan, Guangsheng Tang, Hui Zhang, Zhenglin Jiang. Changes in the gut microbiota during and after commercial helium–oxygen saturation diving in China. Occup Environ Med 2019;76:801

- Mwanaisha Seugendo, Iryna Janssen, Vanessa Lang, Irene Hasibuan, Wolfgang Bohne, Paul Cooper, Rolf Daniel, Katrin Gunka, R. L. Kusumawati, Stephen E. Mshana, Lutz von Müller, Benard Okamo, Jan R. Ortlepp, Jörg Overmann, Thomas Riedel, Maja Rupnik, Ortrud Zimmermann, Uwe Groß. Prevalence and Strain Characterization of Clostridioides (Clostridium) difficile in Representative Regions of Germany, Ghana, Tanzania and Indonesia – A Comparative Multi-Center Cross-Sectional Study. Front. Microbiol. 2018;9

- Keitaro Furukawa, Hiroshi Mitsutake, Ryoko Aso, Ryuichi Sekizawa, Takashi Okanda, Kuniyoshi Hayashi, Tetsuya Matsumoto, Shigeki Nakamura. Usefulness of a newly developed high-speed polymerase chain reaction analysis system for the diagnosis of Clostridioides difficile infection. Journal of Infection and Chemotherapy 2021;27:715

- Xinhua Chen, Xiaotong Yang, Jaime de Anda, Jun Huang, Dan Li, Hua Xu, Kelsey S. Shields, Mária Džunková, Joshua Hansen, Ishan J. Patel, Eric U. Yee, Douglas T. Golenbock, Marianne A. Grant, Gerard C.L. Wong, Ciarán P. Kelly. Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll-Like Receptor 9 Signaling. Gastroenterology 2020;159:2181

- Matthew K. Schnizlein, Vincent B. Young. Capturing the environment of the Clostridioides difficile infection cycle. Nat Rev Gastroenterol Hepatol 2022;19:508

- D.R. Snydman, L.A. McDermott, S.G. Jenkins, E.J.C. Goldstein, R. Patel, B.A. Forbes, S. Johnson, D.N. Gerding, C.M. Thorpe, S.T. Walk. Epidemiologic trends in Clostridioides difficile isolate ribotypes in United States from 2011 to 2016. Anaerobe 2020;63:102185

- Ali Majidpour, Mina Boustanshenas, Samira Rasouli Koohi, Bita Bakhshi, Mohammad Rahbar, Parisa Kiani, Afshin Dinyari, Mastaneh Afshar. Molecular Characterization and Diagnosis of Nosocomial Clostridium difficile Infection in Hospitalized Patients. Arch Clin Infect Dis 2020;15

- Huawei Gu, Yingyin Yang, Meng Wang, Shuyi Chen, Haiying Wang, Shan Li, Yi Ma, Jufang Wang. Novel Cysteine Desulfidase CdsB Involved in Releasing Cysteine Repression of Toxin Synthesis in Clostridium difficile. Front. Cell. Infect. Microbiol. 2018;7

- Tumas Beinortas, Nicholas E Burr, Mark H Wilcox, Venkataraman Subramanian. Comparative efficacy of treatments for Clostridium difficile infection: a systematic review and network meta-analysis. The Lancet Infectious Diseases 2018;18:1035

- J. Intra, D. Carcione, C. Sarto, P. Brambilla. A significant decreased in the frequency of Clostridioides difficile infection at the Italian Hospital of Desio over the last decade. Anaerobe 2021;70:102376

- Soobin Yoon, Junsun Yu, Andrea McDowell, Sung Ho Kim, Hyun Ju You, GwangPyo Ko. Bile salt hydrolase-mediated inhibitory effect of Bacteroides ovatus on growth of Clostridium difficile. J Microbiol. 2017;55:892

- Amanda Nádia Diniz, Carlos Augusto de Oliveira Júnior, Eduardo Garcia Vilela, Henrique Cesar Pereira Figueiredo, Maja Rupnik, Mark H. Wilcox, Warren N. Fawley, Dominique S. Blanc, Francisco Carlos Faria Lobato, Rodrigo Otávio Silveira Silva. Molecular epidemiology of Clostridioides (previously Clostridium) difficile isolates from a university hospital in Minas Gerais, Brazil. Anaerobe 2019;56:34

- Thomas F. Dodson. Invited commentary on Clostridium difficile increases the risk for venous thromboembolism. The American Journal of Surgery 2014;208:710

- Suzana Leite, Carlos Cotias, Kelly C. Rainha, Mayara Gil Santos, Bruno Penna, Renata F. F.Moraes, Céline Harmanus, Wiep Klaas Smits, Eliane de Oliveira Ferreira. Prevalence of Clostridioides difficile in dogs (Canis familiaris) with gastrointestinal disorders in Rio de Janeiro. Anaerobe 2023;83:102765

- Idan Goren, Ortal Fallek Boldes, Tomer Boldes, Oleg Knyazev, Anna Kagramanova, Jimmy K Limdi, Eleanor Liu, Karishma Sethi-Arora, Tom Holvoet, Piotr Eder, Cristina Bezzio, Simone Saibeni, Marta Vernero, Eleonora Alimenti, María Chaparro, Javier P Gisbert, Eleni Orfanoudaki, Ioannis E Koutroubakis, Daniela Pugliese, Giuseppe Cuccia, Cristina Calviño Suarez, Davide Giuseppe Ribaldone, Ido Veisman, Kassem Sharif, Annalisa Aratari, Claudio Papi, Iordanis Mylonas, Gerassimos J Mantzaris, Marie Truyens, Triana Lobaton Ortega, Stéphane Nancey, Fabiana Castiglione, Olga Maria Nardone, Giulio Calabrese, Konstantinos Karmiris, Magdalini Velegraki, Angeliki Theodoropoulou, Ariella Bar-Gil Shitrit, Milan Lukas, Gabriela Vojtechová, Pierre Ellul, Luke Bugeja, Edoardo V Savarino, Tali Sharar Fischler, Iris Dotan, Henit Yanai. Post-Discharge Outcomes of Elderly Patients Hospitalized for Inflammatory Bowel Disease Flare Complicated by Clostridioides difficile Infection. 2024

- Wei Hong, Jie Zhang, Guzhen Cui, Luxin Wang, Yi Wang. Multiplexed CRISPR-Cpf1-Mediated Genome Editing in Clostridium difficile toward the Understanding of Pathogenesis of C. difficile Infection. ACS Synth. Biol. 2018;7:1588

- M. Huart, C. Abat, M.T. Jimeno, X. Deparis, D. Raoult, P.-E. Fournier. Compared lethality rates of Clostridium difficile infections at the local, regional and national levels in France. New Microbes and New Infections 2016;14:6

- Mario Kapitan, M. Joanna Niemiec, Alexander Steimle, Julia S. Frick, Ilse D. Jacobsen. Fungal Physiology and Immunopathogenesis. 2016.

- Giada Fasani, Angela Pieri, Leonardo Pagani. Textbook of Emergency General Surgery. 2016.

- Gloria G. Guerrero M.. Sporulation, Structure Assembly, and Germination in the Soil Bacterium Bacillus thuringiensis: Survival and Success in the Environment and the Insect Host. Microbiology Research 2023;14:466

- Sa'ed H Zyoud. Global research on Clostridium difficile-associated diarrhoea: A visualized study. WJG 2022;28:3720

- A. Romero-Rodríguez, C. Martínez de la Peña, S. Troncoso-Cotal, C. Guzmán, S. Sánchez. Emerging alternatives against Clostridioides difficile infection. Anaerobe 2022;78:102638

- Pamela Medeiros Vieira, Claudia Marques De Lima, Patricia Aparecida Cruz. Nutrição Enteral: elaboração de um protocolo clínico de tratamento de diarreia em Terapia Nutricional Enteral. R. Assoc. bras. Nutr. 2021;12:89

- Micaela Machado Querido, Lívia Aguiar, Paula Neves, Cristiana Costa Pereira, João Paulo Teixeira. Self-disinfecting surfaces and infection control. Colloids and Surfaces B: Biointerfaces 2019;178:8

- Hirokazu Taniguchi, Kumpei Tanisawa, Xiaomin Sun, Takafumi Kubo, Yuri Hoshino, Masahito Hosokawa, Haruko Takeyama, Mitsuru Higuchi. Effects of short‐term endurance exercise on gut microbiota in elderly men. Physiol Rep 2018;6:e13935

- James Collins, Heather Danhof, Robert A. Britton. The role of trehalose in the global spread of epidemicClostridium difficile. Gut Microbes 2019;10:204

- A. D. Reed, M. A. Nethery, A. Stewart, R. Barrangou, C. M. Theriot, Laurie E. Comstock.
Strain-Dependent Inhibition of Clostridioides difficile by Commensal
Clostridia
Carrying the Bile Acid-Inducible (
bai
) Operon
. J Bacteriol 2020;202

- Kjetil Garborg. Anaerobically cultivated human intestinal microbiota as first-line treatment forClostridium difficileinfection. Microbial Ecology in Health & Disease 2015;26

- . UEG Week 2016 Poster Presentations. United European Gastroenterology Journal 2016;4:A157

- Katsunori Yanagihara, Norihiko Akamatsu, Junichi Matsuda, Norihito Kaku, Kiyomitsu Katsumata, Kosuke Kosai. Susceptibility of Clostridium species isolated in Japan to fidaxomicin and its major metabolite OP-1118. Journal of Infection and Chemotherapy 2018;24:492

- Amelia K. Sofjan, Mohammad Aminul Islam, Kakali Halder, Nayel D. Kabir, Ahmed Abu Saleh, Julie Miranda, Chris Lancaster, Khurshida Begum, M. Jahangir Alam, Kevin W. Garey. Molecular epidemiology of toxigenic Clostridioides difficile isolates from hospitalized patients and the hospital environment in Dhaka, Bangladesh. Anaerobe 2020;61:102081

- Francisco A. Uzal, Mauricio A. Navarro, Jihong Li, John C. Freedman, Archana Shrestha, Bruce A. McClane. Comparative pathogenesis of enteric clostridial infections in humans and animals. Anaerobe 2018;53:11

- Hiroshi Sekiya, Yasuhiro Nonaka, Shigehiro Kamitori, Tomomi Miyaji, Eiji Tamai. X-ray structure and mutagenesis analyses of Clostridioides difficile endolysin Ecd09610 glucosaminidase domain. Biochemical and Biophysical Research Communications 2024;715:149957

- Donna M. Schora, Lance R. Peterson, Elena A. Usacheva. Immunological Stability ofClostridium difficileToxins in Clinical Specimens. Infect. Control Hosp. Epidemiol. 2018;39:434

- Adeyinka C. Adejumo, Olalekan Akanbi, Lydie Pani. Among inpatients, ischemic bowel disease predisposes to Clostridium difficile infection with concomitant higher mortality and worse outcomes. 2019;31:109

- David Galloway, Mitchell B. Cohen. Pediatric Gastrointestinal and Liver Disease. 2019.

- Oluwafemi A Ajibola, Taiwo O Aremu, Sikder Hassan, Nili Gujadhur, Valerie Cluzet. An Unusual Presentation of Clostridioides Difficile Colitis in a Patient on Opioids. 2022

- Tongxuan Su, Wei Chen, Daosheng Wang, Yingchao Cui, Qi Ni, Cen Jiang, Danfeng Dong, Yibing Peng. Complete Genome Sequencing and Comparative Phenotypic Analysis Reveal the Discrepancy Between Clostridioides difficile ST81 and ST37 Isolates. Front. Microbiol. 2021;12

- Joana Darc Freitas Alves, Augusto Yamaguti, João Silva de Mendonça, Cristiano de Melo Gamba, Cibele Lefreve Fonseca, Daniela K. S. Paraskevopoulos, Alexandre Inacio de Paula, Nair Hosino, Silvia Figueiredo Costa, Thaís Guimarães. Metronidazole for Treatment of Clostridioides difficile Infections in Brazil: A Single-Center Experience and Risk Factors for Mortality. Antibiotics 2022;11:1162

- Can M Ünal, Michael Steinert. Novel therapeutic strategies for Clostridium difficile infections. Expert Opinion on Therapeutic Targets 2016;20:269

- Zhen Zeng, Hailong Zhao, Mary Beth Dorr, Judong Shen, Mark H. Wilcox, Ian R. Poxton, Dalya Guris, Junhua Li, Peter M. Shaw. Bezlotoxumab for prevention of Clostridium difficile infection recurrence: Distinguishing relapse from reinfection with whole genome sequencing. Anaerobe 2020;61:102137

- Elie Chouillard, Marc-Anthony Chouillard, Nader El Kary, Belinda De Simone, Andrew A. Gumbs. Clostridium difficile infection secondary to ileostomy closure. Mini-invasive Surg 2021

- Sophia Julia Häfner. Sweet dreams: How mini-invasive surgery tackles obstructive sleep apnea. Biomedical Journal 2019;42:75

- Jung Hwa Min, You Sun Kim. Proton Pump Inhibitors Should be Used with Caution in Critically Ill Patients to Prevent the Risk of Clostridium difficile Infection. Gut and Liver 2016;10:493

- Sylwia Dudzicz, Marcin Adamczak, Andrzej Więcek. Clostridium difficile infection in patients after solid organ transplantations. Postepy Hig Med Dosw 2020;74:198

- Jane Leung, Stacey Pham. A Systematic Review of Fecal Microbiota Transplantation Versus Vancomycin for Treatment of Recurrent Clostridioides difficile Infection. 2021;44:106

- Nazila V. Jafari, Mario Songane, Richard A. Stabler, Mamoun Elawad, Brendan W. Wren, Elaine Allan, Mona Bajaj-Elliott, S. R. Blanke. Host Immunity to Clostridium difficile PCR Ribotype 017 Strains. Infect Immun 2014;82:4989

- D. S. Purgina, L. V. Lyalina, V. V. Rassokhin. Clostridium diffi cile infection and its eff ect on the course of infl ammatory bowel diseases. jour 2022;100:346

- Abhilasha Bhargava, Chandrashekhar Mahakalkar, Shivani Kshirsagar, Akanksha Yachmaneni. Toxic Megacolon: A Sequelae of Clostridioides difficile Infection in a Case of Necrotizing Fasciitis. 2024

- Lillian Yu, Reynal Palafox-Rosas, Brian Luna, Rosemary C. She. The Bactericidal Activity and Spore Inhibition Effect of Manuka Honey against Clostridioides Difficile. Antibiotics 2020;9:684

- Igor G. Bakulin, Irina A. Rasmagina, Maria I. Skalinskaya. Diagnosis and prognosis of inflammatory bowel diseases: modern view. HERALD of North-Western State Medical University named after I.I. Mechnikov 2021;13:19

- Heera Jeong, Ji-Man Kang, Jong Gyun Ahn. Incidence and Characteristics ofClostridioides difficileInfection in Children. Pediatr Infect Vaccine 2020;27:158

- Ji Hyun Yun, Ga Eun Park, Hyun Kyun Ki. Correlation between antibiotic consumption and the incidence of healthcare facility-onset Clostridioides difficile infection: a retrospective chart review and analysis. Antimicrob Resist Infect Control 2021;10

- Sharon A Greenberg, Ilan Youngster, Nathaniel A Cohen, Dan M Livovsky, Jacob Strahilevitz, Eran Israeli, Ehud Melzer, Kalman Paz, Naomi Fliss-Isakov, Nitsan Maharshak. Five years of fecal microbiota transplantation - an update of the Israeli experience. WJG 2018;24:5403

- Marta Mattana, Riccardo Tomasello, Claudia Cammarata, Paola Di Carlo, Teresa Fasciana, Giulio Giordano, Alessandro Lucchesi, Sergio Siragusa, Mariasanta Napolitano. Clostridium difficile Induced Inflammasome Activation and Coagulation Derangements. Microorganisms 2022;10:1624

- Chunyan Zhao, Guangxin Guo, Zhaoxin Li, Jiaxu Chen, Yichao Ren. Effects of probiotics (Bacillus coagulans) supplementation after antibiotic administration on growth, immunity, and intestinal microflora in turbot Scophthalmus maximus. Aquacult Int 2024;32:1473

- Amanda Cano, Miren Ettcheto, Marta Espina, Ana López-Machado, Yolanda Cajal, Francesc Rabanal, Elena Sánchez-López, Antonio Camins, Maria Luisa García, Eliana B. Souto. State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections. J Nanobiotechnol 2020;18

- Samantha C. Kisthardt, Rajani Thanissery, Colleen M. Pike, Matthew H. Foley, Casey M. Theriot, Tina M. Henkin.
The microbial-derived bile acid lithocholate and its epimers inhibit
Clostridioides difficile
growth and pathogenicity while sparing members of the gut microbiota
. J Bacteriol 2023;205

- J. Mattner, F. Schmidt, B. Siegmund. Faecal microbiota transplantation—A clinical view. International Journal of Medical Microbiology 2016;306:310

- M. Gilboa, E. Houri-Levi, C. Cohen, I. Tal, C. Rubin, O. Feld-Simon, A. Brom, Y. Eden-Friedman, S. Segal, G. Rahav, G. Regev-Yochay, Howard Amital, Sharon Beni, Ilan Ben-Zvi, Natasha Blausov, Adi Brom, Carmit Cohen, Olga Feld-Simon, Ronen Fluss, Mayan Gilboa, Yehudit Eden-Friedman, Shiraz Halevy, Esther Houri-Levi, Amit Hupert, Amnah Jbarien, Naty Keller, Avshalom Leibowitz, Haim Mayan, Leonid Maizels, Eyal Meltzer, Nani Pinas-Zade, Galia Rahav, Shir Raibman-Spector, Gili Regev-Yochay (PI), Marina Romiantsev, Dalit Shachar, Kassem Sharif, Gadi Segal, Shoshi Segal, Amitai Segev, Gill Smollan, Shmuel Stienlauf, Ilana Tal, Hagit Yonath, Tal Zilberman-Daniels, Eyal Zimlichman. Environmental shedding of toxigenic Clostridioides difficile by asymptomatic carriers: A prospective observational study. Clinical Microbiology and Infection 2020;26:1052

- Masayoshi Sato, Kazuyuki Fujii, Hiroko Takagi, Isao Shibuya, Daisuke Oka, Naomitsu Yamaya, Hiraku Hagita, Makoto Matsumoto, Katsuya Inagaki. Antibacterial and Immunosuppressive Effects of OPS-2071, a Candidate Therapy for Inflammatory Bowel Disease. Dig Dis Sci 2022;67:3993

- Siti Rabiatul Fajri, Sucika Armiani, Akhmad Sukri, Ibnu Maryanto, Bambang Fajar Suryadi, Zainul Muttaqin. New Report: An Overview of Bats Bacteria And Its Implication For Tourism In KEK Mandalika, Lombok Island West Nusa Tenggara - Indonesia. IOP Conf. Ser.: Earth Environ. Sci. 2024;1425:012022

- Thomas Lavoie, Haley J Appaneal, Kerry L LaPlante. Advancements in Novel Live Biotherapeutic Products for Clostridioides difficile Infection Prevention. 2023;77:S447

- Hiroshi Sekiya, Saki Kobayashi, Ikumi Takahashi, Shigehiro Kamitori, Eiji Tamai. Biochemical Characterizations of the Putative Amidase Endolysin Ecd18980 Catalytic Domain from Clostridioides difficile. Biological & Pharmaceutical Bulletin 2023;46:1625

- Ola H. Negm, Mohamed R. Hamed, Elizabeth M. Dilnot, Clifford C. Shone, Izabela Marszalowska, Mark Lynch, Christine E. Loscher, Laura J. Edwards, Patrick J. Tighe, Mark H. Wilcox, Tanya M. Monaghan, R. L. Hodinka. Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis. Clin Vaccine Immunol 2015;22:1033

- Takahiko NAGAMINE, Yoshinobu MATSUMOTO, Masaru NAKAMURA. Combination probiotics may prevent Clostridium difficile infection among elderly patients undergoing an orthopedic surgery. 2019;38:31

- Bar Levy, Naomi Fliss Isakov, Tomer Ziv-Baran, Moshe Leshno, Nitsan Maharshak, Lael Werner. Economic and Chronologic Optimization of Fecal Donors Screening Process. MDM Policy & Practice 2024;9

- Christian Eckmann, Sue Lyon.
ECCMID 2016: Addressing the Burden of Recurrent
Clostridium Difficile
Infections
. Future Microbiol. 2016;11:1217

- Meenakshi Singh, Chetana Vaishnavi, Safrun Mahmood, Rakesh Kochhar. Toxinotyping and Sequencing of Clostridium difficile Isolates from Patients in a Tertiary Care Hospital of Northern India. Front. Med. 2017;4

- Wasef Na’amnih, Amos Adler, Tamar Miller-Roll, Dani Cohen, Yehuda Carmeli. Incidence and Risk Factors for Community and Hospital Acquisition of Clostridium difficile Infection in the Tel Aviv Sourasky Medical Center. Infect. Control Hosp. Epidemiol. 2017;38:912

- Jung Hoon Song, You Sun Kim. RecurrentClostridium difficileInfection: Risk Factors, Treatment, and Prevention. Gut and Liver 2019;13:16

- Shan-Shan Jiang, Wei Liu, Li Liu, Yun Bai. Severe complicated Clostridium difficile infection: A case report. WCJD 2020;28:308

- Yifan Wang, Aaron Hunt, Larry Danziger, Emily N. Drwiega. A Comparison of Currently Available and Investigational Fecal Microbiota Transplant Products for Recurrent Clostridioides difficile Infection. Antibiotics 2024;13:436

- Jinqiu Liu, Wei Zhu, Duncan James Lessing, Weihua Chu. Synthetic microbial consortia for the treatment of Clostridioides difficile infection in mice model. Microbial Biotechnology 2023;16:1985

- I Na Yoon, Li Fang Lu, Ji Hong, Peng Zhang, Dae Hong Kim, Jin Ku Kang, Jae Sam Hwang, Ho Kim. The American cockroach peptide periplanetasin‐4 inhibits Clostridium difficile toxin A‐induced cell toxicities and inflammatory responses in the mouse gut. Journal of Peptide Science 2017;23:833

- Ayham Khrais, Anna G Mathew, Aaron Kahlam, Alexander Le, Anmol Mittal, Siddharth Verma. Investigating the Correlation Between Clostridioides difficile Infection and Vitamin D Deficiency. 2023

- A. McLure, A.C.A. Clements, M. Kirk, K. Glass. Clostridium difficile classification overestimates hospital-acquired infections. Journal of Hospital Infection 2018;99:453

- Deyan Luo, Xuechao Liu, Li Xing, Yakun Sun, Jie Huang, Liangyan Zhang, Jiajia Li, Hui Wang. Immunogenicity and Protection from Receptor-Binding Domains of Toxins as Potential Vaccine Candidates for Clostridium difficile. Vaccines 2019;7:180

- Dan Nicolae Păduraru, Daniel Ion, Mihai Dumitrașcu, Răzvan Petca, Aida Petca, Florica Șandru, Octavian Andronic, Georgiana Radu, Alexandra Bolocan. Clostridium difficile infection characteristics in a general surgery clinic. Exp Ther Med 2021;22

- Rumyana Markovska, Georgi Dimitrov, Raina Gergova, Lyudmila Boyanova. Clostridioides difficile, a New “Superbug”. Microorganisms 2023;11:845

- Husnu Sahan Guran, Osman Irfan Ilhak. Clostridium difficile in retail chicken meat parts and liver in the Eastern Region of Turkey. J. Verbr. Lebensm. 2015;10:359

- Ilan Youngster, Dale N Gerding. Editorial: Making Fecal Microbiota Transplantation Easier to Swallow: Freeze-Dried Preparation for Recurrent Clostridium difficile Infections. 2017;112:948

- Osamu Matsuoka, Dhaval M. Patel, Shin Sasaki, Hayato Oka, Toru Sasaki, Patricia J. Pietrobon, Thelma Laot, Alain Bouckenooghe, Josemund Menezes, Guy de Bruyn. Safety and immunogenicity of Clostridium difficile toxoid vaccine in Japanese adults. Human Vaccines & Immunotherapeutics 2018;14:322

- S. Gemein, B. Meyer, J. Gebel, C. Roques, K. Steinhauer. Response to J-Y. Maillard: Are amine-only-containing products sporicidal?. Journal of Hospital Infection 2018;100:e68

- Adam Cheknis, Dominique Devaris, Laurent Chesnel, Suzanne E Dale, Julia Nary, Susan P Sambol, Diane M Citron, Richard V Goering, Stuart Johnson. Characterization of Clostridioides difficile isolates recovered from two Phase 3 surotomycin treatment trials by restriction endonuclease analysis, PCR ribotyping and antimicrobial susceptibilities. 2020;75:3120

- Qianyun Lin, Nira R Pollock, Alice Banz, Aude Lantz, Hua Xu, Limei Gu, Dale N Gerding, Kevin W Garey, Anne J Gonzales-Luna, Mingwei Zhao, Linan Song, David C Duffy, Ciaran P Kelly, Xinhua Chen. Toxin A–Predominant Pathogenic Clostridioides difficile: A Novel Clinical Phenotype. 2020;70:2628

- Ana Gutiérrez-Preciado, Alfredo Gabriel Torres, Enrique Merino, Hernán Ruy Bonomi, Fernando Alberto Goldbaum, Víctor Antonio García-Angulo, Gabriel Moreno-Hagelsieb. Extensive Identification of Bacterial Riboflavin Transporters and Their Distribution across Bacterial Species. PLoS ONE 2015;10:e0126124

- Hamideh Raeisi, Masoumeh Azimirad, Hamid Asadzadeh Aghdaei, Abbas Yadegar, Mohammad Reza Zali. Rapid-format recombinant antibody-based methods for the diagnosis of Clostridioides difficile infection: Recent advances and perspectives. Front. Microbiol. 2022;13

- BRUNO AMANTINI MESSIAS, BÁRBARA FREITAS FRANCHI, PEDRO HENRIQUE PONTES, DANIEL ÁTILA DE ANDRADE MEDEIROS BARBOSA, CÉSAR AUGUSTO SANITA VIANA. Fecal microbiota transplantation in the treatment of Clostridium difficile infection: state of the art and literature review. Rev. Col. Bras. Cir. 2018;45

- Enzo Guerrero-Araya, Claudio Meneses, Eduardo Castro-Nallar, Ana M. Guzmán D., Manuel Álvarez-Lobos, Carlos Quesada-Gómez, Daniel Paredes-Sabja, César Rodríguez. Origin, genomic diversity and microevolution of the Clostridium difficile B1/NAP1/RT027/ST01 strain in Costa Rica, Chile, Honduras and Mexico. 2020;6

- Anna Voziki, Olga Deda, Melania Kachrimanidou. The Efficacy of Fecal Microbiota Transplantation in Mouse Models Infected with Clostridioides difficile from the Perspective of Metabolic Profiling: A Systematic Review. Metabolites 2024;14:677

- Uday C Ghoshal, Kok‐Ann Gwee, Gerald Holtmann, Yanmei Li, Soo Jung Park, Marcellus Simadibrata, Kentaro Sugano, Kaichun Wu, Eamonn M M Quigley, Henry Cohen. The role of the microbiome and the use of probiotics in gastrointestinal disorders in adults in the Asia‐Pacific region ‐ background and recommendations of a regional consensus meeting. J of Gastro and Hepatol 2018;33:57

- Nigel George Ternan, Nicola Diana Moore, Deborah Smyth, Gordon James McDougall, James William Allwood, Susan Verrall, Christopher Ian Richard Gill, James Stephen Gerard Dooley, Geoff McMullan. Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity. Sci Rep 2018;8

- Guglielmo Borgia, Alberto Enrico Maraolo, Maria Foggia, Antonio Riccardo Buonomo, Ivan Gentile. Fecal microbiota transplantation forClostridium difficileinfection: back to the future. Expert Opinion on Biological Therapy 2015;15:1001

- Wan Wang, Cong Xu, Zhijing Liu, Liya Gu, Jiage Ma, Juncai Hou, Zhanmei Jiang. Physicochemical properties and bioactivity of polysaccharides from Isaria cicadae Miquel with different extraction processes: effects on gut microbiota and immune response in mice. Food Funct. 2022;13:9268

- Amanda Nádia Diniz, Diogo Soares Gonçalves Cruz, Carolina Pantuzza Ramos, Carlos Augusto Oliveira Júnior, Isabella Caixeta Winter, Jorge Tibúrcio Barbosa de Lima, Armando de Mattos Carvalho, Francisco Carlos Faria Lobato, Rodrigo Otávio Silveira Silva. Clostridioides (Clostridium) difficile-associated diarrhea in equine in Minas Gerais, Brazil: clinical and microbiological characterization of six cases. Cienc. Rural 2021;51

- Genady Drozdinsky, Alaa Atamna, Hagar Banai, Haim Ben-Zvi, Jihad Bishara, Noa Eliakim-Raz. Clinical outcomes for Clostridioides difficile associated diarrhea in inflammatory bowel disease patients versus non-IBD population: A retrospective cohort study. 2023;102:e32812

- Nienke Z. Borren, Shadi Ghadermarzi, Susan Hutfless, Ashwin N. Ananthakrishnan, Abhishek Deshpande. The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact. PLoS ONE 2017;12:e0176797

- Reem AlJindan, Doaa M AlEraky, J. Francis Borgio, Sayed AbdulAzeez, Baha Abdalhamid, Nehal Mahmoud, Maha Farhat. Diagnostic deficiencies of C. difficile infection among patients in a tertiary hospital in Saudi Arabia: A laboratory-based case series. Saudi Journal of Biological Sciences 2021;28:4472

- Nienke Koopman, Lauren Remijas, Jurgen Seppen, Peter Setlow, Stanley Brul. Mechanisms and Applications of Bacterial Sporulation and Germination in the Intestine. IJMS 2022;23:3405

- Prashanna Balaji Venkatasubramanian, Els Oosterink, Monic M. M. Tomassen, Maria Suarez-Diez, Jurriaan J. Mes, Edoardo Saccenti, Nicole J. W. de Wit. Transcriptome-based identification of the beneficial role of blackcurrant, strawberry and yellow onion to attenuate the cytopathic effects of Clostridium difficile toxins. Journal of Berry Research 2021;11:231

- Neil Boudville, David W Johnson, Junhui Zhao, Brian A Bieber, Ronald L Pisoni, Beth Piraino, Judith Bernardini, Sharon J Nessim, Yasuhiko Ito, Graham Woodrow, Fiona Brown, John Collins, Talerngsak Kanjanabuch, Cheuk-Chun Szeto, Jeffrey Perl. Regional variation in the treatment and prevention of peritoneal dialysis-related infections in the Peritoneal Dialysis Outcomes and Practice Patterns Study. 2019;34:2118

- Jessica E. Buddle, Robert P. Fagan.
Pathogenicity and virulence of
Clostridioides difficile
. Virulence 2023;14

- Christianne Maria Tinoco-Veras, Ana Angélica Q. A. Santos, Joice Stipursky, Marcelo Meloni, Ana Paula Bérgamo Araujo, Danielle Abreu Foschetti, Diana López-Ureña, Carlos Quesada-Gómez, Renata F. C. Leitão, Flávia Carvalho Alcantara Gomes, Gerly Anne de Castro Brito, Vincent B. Young. Transforming Growth Factor β1/SMAD Signaling Pathway Activation Protects the Intestinal Epithelium from Clostridium difficile Toxin A-Induced Damage. Infect Immun 2017;85

- Mareike Berges, Annika-Marisa Michel, Christian Lassek, Aaron M. Nuss, Michael Beckstette, Petra Dersch, Katharina Riedel, Susanne Sievers, Dörte Becher, Andreas Otto, Sandra Maaß, Manfred Rohde, Denitsa Eckweiler, Jose M. Borrero-de Acuña, Martina Jahn, Meina Neumann-Schaal, Dieter Jahn. Iron Regulation in Clostridioides difficile. Front. Microbiol. 2018;9

- Syeda Sahra, Abdullah Jahangir, Vincent De Chavez. Antimicrobial Stewardship: A Review for Internal Medicine Physicians. 2021

- Yi-Hsuan Su, Ali Rohani, Cirle A. Warren, Nathan S. Swami. Tracking Inhibitory Alterations during Interstrain Clostridium difficile Interactions by Monitoring Cell Envelope Capacitance. ACS Infect. Dis. 2016;2:544

- Marcelo José Barbosa Silva, Matheus Batista Heitor Carneiro, Brunna dos Anjos Pultz, Danielle Pereira Silva, Mateus Eustáquio de Moura Lopes, Liliane Martins dos Santos. The Multifaceted Role of Commensal Microbiota in Homeostasis and Gastrointestinal Diseases. Journal of Immunology Research 2015;2015:1

- Weiling Guo, Xin Tang, Qiuxiang Zhang, Feifei Xiong, Yongqiu Yan, Jianxin Zhao, Bingyong Mao, Hao Zhang, Shumao Cui. Lacticaseibacillus paracasei CCFM1222 Ameliorated the Intestinal Barrier and Regulated Gut Microbiota in Mice with Dextran Sulfate Sodium-Induced Colitis. Probiotics & Antimicro. Prot. 2024

- Zhihong Liu, Xiaofang Liang, Yu Zhang, Wenbo Deng, Yulin Wang, Zhangping Lu, Qianqian Liu, Lianhua Wei. Drug Repurposing: Research Progress of Niclosamide and Its Derivatives on Antibacterial Activity. IDR 2024;Volume 17:4539

- Monica Rosas-Lemus, Supratim Dey, George Minasov, Kemin Tan, Spencer M. Anderson, Joseph Brunzelle, Salvatore Nocadello, Ivan Shabalin, Ekaterina Filippova, Andrei Halavaty, Youngchang Kim, Natalia Maltseva, Jerzy Osipiuk, Wladek Minor, Andrzej Joachimiak, Alexei Savchenko, Wayne F. Anderson, Karla J. F. Satchell, Irene L. G. Newton.
A high-throughput structural system biology approach to increase structure representation of proteins from
Clostridioides difficile
. Microbiol Resour Announc 2023;12

- C. M. Thorpe, L. A. McDermott, M. K. Tran, J. Chang, S. G. Jenkins, E. J. C. Goldstein, R. Patel, B. A. Forbes, S. Johnson, D. N. Gerding, D. R. Snydman. U.S.-Based National Surveillance for Fidaxomicin Susceptibility of Clostridioides difficile-Associated Diarrheal Isolates from 2013 to 2016. Antimicrob Agents Chemother 2019;63

- Jana G. Hashash, David G. Binion. Managing Clostridium difficile in Inflammatory Bowel Disease (IBD). Curr Gastroenterol Rep 2014;16

- Maribeth Nicholson, Isaac Thomsen, Kathryn Edwards. Controversies Surrounding Clostridium difficile Infection in Infants and Young Children. Children 2014;1:40

- Yi‐Ming Chen, Chen‐Chung Liao, Yen‐Chun Huang, Ming‐Yi Chen, Chi‐Chang Huang, Wen‐Chyuan Chen, Yen‐Shuo Chiu. Proteome and microbiota analysis highlight Lactobacillus plantarum TWK10 supplementation improves energy metabolism and exercise performance in mice. Food Science & Nutrition 2020;8:3525

- Rajesh Venkataraman, Umesh Yadav, Ravi Kurikempannadoddi Shivalingegowda, Yogendra Shrestha. Vaccination strategies to combat nosocomial infections. Vacunas (English Edition) 2023;24:60

- Evdokia Pourliotopoulou, Theodoros Karampatakis, Melania Kachrimanidou. Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection. Microorganisms 2024;12:1004

- Zhong Peng, Sidi Liu, Xiujuan Meng, Wan Liang, Zhuofei Xu, Biao Tang, Yuanguo Wang, Juping Duan, Chenchao Fu, Bin Wu, Anhua Wu, Chunhui Li. Genome characterization of a novel binary toxin-positive strain of Clostridium difficile and comparison with the epidemic 027 and 078 strains. Gut Pathog 2017;9

- . Diagnostic Imaging: Gastrointestinal. 2017.

- Mattias E. Ivarsson, Jean-Christophe Leroux, Bastien Castagner. Investigational new treatments for Clostridium difficile infection. Drug Discovery Today 2015;20:602

- D. R. Snydman, L. A. McDermott, C. M. Thorpe, E. J. C. Goldstein, A. N. Schuetz, S. Johnson, D. N. Gerding, L. Gluck, D. Bourdas, K. C. Carroll, C. K. Lancaster, K. W. Garey, Q. Wang, S. T. Walk, E. Duperchy, Jared A. Silverman.
A US-based national surveillance study for the susceptibility and epidemiology of
Clostridioides difficile
isolates with special reference to ridinilazole: 2020–2021
. Antimicrob Agents Chemother 2023;67

- Gurinder K. Vinner, Goran T. Vladisavljević, Martha R. J. Clokie, Danish J. Malik, Etienne Dague. Microencapsulation of Clostridium difficile specific bacteriophages using microfluidic glass capillary devices for colon delivery using pH triggered release. PLoS ONE 2017;12:e0186239

- Rita D. Shelby, Natalie Tengberg, Miriam Conces, Jacob K. Olson, Jason B. Navarro, Michael T. Bailey, Steven D. Goodman, Gail E. Besner. Development of a Standardized Scoring System to Assess a Murine Model of Clostridium difficile Colitis. Journal of Investigative Surgery 2020;33:887

- Andrei Dudun, Dariana Chesnokova, Vera Voinova, Anton Bonartsev, Garina Bonartseva. Changes in the Gut Microbiota Composition during Implantation of Composite Scaffolds Based on Poly(3-hydroxybutyrate) and Alginate on the Large-Intestine Wall. Polymers 2023;15:3649

- Motoi Nomura, Taisuke Kuroda, Norihisa Tamura, Masanori Muranaka, Hidekazu Niwa. Mortality, clinical findings, predisposing factors and treatment ofClostridioides difficilecolitis in Japanese thoroughbred racehorses. Veterinary Record 2020;187

- Birbal Singh, Gorakh Mal, Rajkumar Singh Kalra, Francesco Marotta. Probiotics as Live Biotherapeutics for Veterinary and Human Health, Volume 2. 2020.

- UZhe Ding, Lijin Ooi, Henry H. L. Wu, Rajkumar Chinnadurai. Clostridioides difficile Infection in Kidney Transplant Recipients. Pathogens 2024;13:140

- Pil Hun Song, Jung Hwa Min, You Sun Kim, Soo Yeon Jo, Eun Jin Kim, Kyung Jin Lee, Jeonghun Lee, Hyun Sung, Jeong Seop Moon, Dong Hee Whang. Rapid and accurate diagnosis of Clostridium difficile infection by real-time polymerase chain reaction. Intest Res 2018;16:109

- Can Murat Ünal, Mareike Berges, Nathiana Smit, Cordelia Schiene-Fischer, Christina Priebe, Till Strowig, Dieter Jahn, Michael Steinert. PrsA2 (CD630_35000) of Clostridioides difficile Is an Active Parvulin-Type PPIase and a Virulence Modulator. Front. Microbiol. 2018;9

- Vanessa W. Stevens, Ellyn M. Russo, Yinong Young-Xu, Molly Leecaster, Yue Zhang, Chong Zhang, Holly Yu, Bing Cai, Elisa N. Gonzalez, Dale N. Gerding, Jody Lawrence, Matthew H. Samore. Identification of patients at risk of Clostridioides difficile infection for enrollment in vaccine clinical trials. Vaccine 2021;39:536

- Madeleine Kleven. Excrement Strikes Back: The Dark Side of Fecal Microbiota Transplantation. Korean J Healthc Assoc Infect Control Prev 2019;24:108
