Gut and Liver 2009; 3(1): 35-40 https://doi.org/10.5009/gnl.2009.3.1.35 Colorectal Neoplasm in Asymptomatic Average-risk Koreans: The KASID Prospective Multicenter Colonoscopy Survey
Author Information
Hye-Won Park*, Jeong-Sik Byeon*, Suk-Kyun Yang*, Hyun Soo Kim, Won Ho Kim, Tae Il Kim, Dong Il Park§, Young-Ho Kim§, Hyo Jong Kim, Moon Sung Lee, Il-Kwon Chung, Sung-Ae Jung#, Yoon Tae Jeen**, Jai Hyun Choi**, Hwang Choi††, Kyu Yong Choi††, Dong Soo Han‡‡, and Jae Suk Song§§
Department of Internal Medicine, *Asan Medical Center, University of Ulsan College of Medicine, Seoul, Yonsei University Wonju College of Medicine, Wonju, Yonsei University College of Medicine, Seoul, §Sungkyunkwan University College of Medicine, Seoul, Kyunghee University College of Medicine, Seoul, Soonchunhyang University College of Medicine, Bucheon and Cheonan, #Ewha Woman's University College of Medicine, Seoul, **Korea University College of Medicine, Seoul and Ansan, ††The Catholic University College of Medicine, Incheon, ‡‡Hanyang University College of Medicine, Guri, and §§Department of Preventive Medicine, Kwandong University College of Medicine, Gangneung, Korea

Jeong-Sik Byeon
© The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. All rights reserved.

Abstract
Background/Aims: The incidence of colorectal cancer is increasing in Korea, but the epidemiology of colorectal neoplasm is not clearly defined. We aimed to elucidate the prevalence of colorectal neoplasm in average-risk Koreans and explore the underlying risk factors. Methods: A large-scale, multicenter, prospective study was conducted. Of the 19,460 subjects who underwent colonoscopy at 11 university hospitals, we analyzed 3,951 consecutive asymptomatic adults with no risk factors for colorectal cancer. Results: The subjects were aged 52.1±11.6 years (mean±SD) and 60.1% of them were men. The prevalences of colorectal neoplasm and advanced neoplasm were 33.3% and 2.2%, respectively. The prevalence of a neoplasm increased with age (trend: p<0.001) and was higher in males (p<0.001). The prevalence of a proximal neoplasm was higher in subjects with a distal neoplasm than in those without a distal neoplasm (11.9% vs. 5.4%, p<0.001). However, 150 (52.1%) of the 288 subjects with a proximal neoplasm had no distal neoplasm. Conclusions: The overall prevalence of colorectal neoplasm in asymptomatic average-risk Koreans is comparable with that in Western countries. Being male and older are associated with a higher risk of colorectal neoplasm. Over half of proximal neoplasms are not associated with any distal sentinel lesions. (Gut and Liver 2009;3:35-40)
Keywords: Prevalence; Colonoscopy; Colorectal neoplasms; Korea; Mass screening
Abstract
Background/Aims: The incidence of colorectal cancer is increasing in Korea, but the epidemiology of colorectal neoplasm is not clearly defined. We aimed to elucidate the prevalence of colorectal neoplasm in average-risk Koreans and explore the underlying risk factors. Methods: A large-scale, multicenter, prospective study was conducted. Of the 19,460 subjects who underwent colonoscopy at 11 university hospitals, we analyzed 3,951 consecutive asymptomatic adults with no risk factors for colorectal cancer. Results: The subjects were aged 52.1±11.6 years (mean±SD) and 60.1% of them were men. The prevalences of colorectal neoplasm and advanced neoplasm were 33.3% and 2.2%, respectively. The prevalence of a neoplasm increased with age (trend: p<0.001) and was higher in males (p<0.001). The prevalence of a proximal neoplasm was higher in subjects with a distal neoplasm than in those without a distal neoplasm (11.9% vs. 5.4%, p<0.001). However, 150 (52.1%) of the 288 subjects with a proximal neoplasm had no distal neoplasm. Conclusions: The overall prevalence of colorectal neoplasm in asymptomatic average-risk Koreans is comparable with that in Western countries. Being male and older are associated with a higher risk of colorectal neoplasm. Over half of proximal neoplasms are not associated with any distal sentinel lesions. (Gut and Liver 2009;3:35-40)
Keywords: Prevalence; Colonoscopy; Colorectal neoplasms; Korea; Mass screening
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