Gut and Liver 2007; 1(2): 182-185 https://doi.org/10.5009/gnl.2007.1.2.182 Acute Myeloid Leukemia Presenting as Obstructive Jaundice Caused by Granulocytic Sarcoma
Author Information
Joo Young Lee*, Wan Suk Lee*, Min Kyu Jung*, Seong Woo Jeon*, Chang Min Cho*, Won Young Tak*, Young Oh Kweon*, Sung Kook Kim*, Yong Hwan Choi*, Jong Gwang Kim, and Sang Kyun Sohn
Divisions of *Gastroenterology and Hepatology and Hematology and Oncology, Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea

Chang Min Cho
© The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. All rights reserved.

Abstract
We report a rare case of granulocytic sarcoma infiltrating the bile duct in a patient with acute myeloid leukemia. A 23-year-old man presented with jaundice and weight loss. A peripheral blood smear revealed blast cells, and the results of an examination of bone marrow aspirate were consistent with acute myeloid leukemia. The bilirubin level increased gradually after induction chemotherapy with cytarabine. Magnetic resonance cholangiopancreatography (MRCP) revealed dilatation of the intrahepatic bile ducts and smooth tapering off at the level of the common hepatic bile duct. Endoscopic retrograde cholangiopancreatography (ERCP) also revealed diffuse narrowing of the proximal common hepatic bile duct. Obstructive jaundice resolved after endoscopic nasobiliary drainage. Remission induction chemotherapy with cytarabine and idarubicin was administered, and the patient remained complete hematological remission with normal liver function tests. (Gut and Liver 2007;1:182-185)
Keywords: Leukemia, Myelocytic, Acute; Jaundice, Obstructive; Bile ducts; Retrograde cholangiopancreatography, Endoscopic
Abstract
We report a rare case of granulocytic sarcoma infiltrating the bile duct in a patient with acute myeloid leukemia. A 23-year-old man presented with jaundice and weight loss. A peripheral blood smear revealed blast cells, and the results of an examination of bone marrow aspirate were consistent with acute myeloid leukemia. The bilirubin level increased gradually after induction chemotherapy with cytarabine. Magnetic resonance cholangiopancreatography (MRCP) revealed dilatation of the intrahepatic bile ducts and smooth tapering off at the level of the common hepatic bile duct. Endoscopic retrograde cholangiopancreatography (ERCP) also revealed diffuse narrowing of the proximal common hepatic bile duct. Obstructive jaundice resolved after endoscopic nasobiliary drainage. Remission induction chemotherapy with cytarabine and idarubicin was administered, and the patient remained complete hematological remission with normal liver function tests. (Gut and Liver 2007;1:182-185)
Keywords: Leukemia, Myelocytic, Acute; Jaundice, Obstructive; Bile ducts; Retrograde cholangiopancreatography, Endoscopic
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