Gut and Liver 2011; 5(1): 115-116 https://doi.org/10.5009/gnl.2011.5.1.115 Contrast Does Not Affect Cholangioscope Image Quality
Author Information
Jeffrey Laczek*, Mark Flasar, Eric Goldberg, and Peter Darwin
*Gastroenterology Service, Department of Medicine, Walter Reed Army Medical Center, Washington, DC, Division of Gastroenterology, University of Maryland Medical Center, Baltimore, Maryland, USA

Jeffrey Laczek
© The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. All rights reserved.

Abstract
Background/Aims: Peroral cholangioscopy is a rapidly evolving technique that allows direct examination of the bile duct. We sought to determine if there was a difference in image quality with the cholangioscope immersed in normal saline compared with radiologic contrast or a mixture of contrast and normal saline. Methods: Images were captured using the SpyGlass?cholangioscope system (Boston Scientific Corp.) immersed in solutions ranging from 0 to 100% contrast. The images were then reviewed in a blinded fashion by a panel of 9 endoscopists with experience using the SpyGlass?system. The reviewers scored the quality of each image based on a scale of 0 (extremely poor) to 10 (excellent). Results: With the cholangioscope immersed in saline and 100% contrast, the mean image quality scores were 7.6 (95% confi dence interval [CI], 6.7-8.5) and 6.9 (95% CI, 5.8-8.0), respectively. The highest mean image quality score was 7.8 (95% CI, 6.7-8.9), obtained in 70% contrast. No signifi cant difference was noted in mean image quality scores using a one way analysis of variance technique (p=0.414). Conclusions: Although there are limitations to ex vivo studies, we encourage endoscopists to use intraductal contrast prior to peroral cholangioscopy, if needed for lesion localization. (Gut Liver 2011;5:115-116)
Keywords: Bile ducts; Endoscopes; Cho langiopancreatography; Endoscopic retrograde
Abstract
Background/Aims: Peroral cholangioscopy is a rapidly evolving technique that allows direct examination of the bile duct. We sought to determine if there was a difference in image quality with the cholangioscope immersed in normal saline compared with radiologic contrast or a mixture of contrast and normal saline. Methods: Images were captured using the SpyGlass?cholangioscope system (Boston Scientific Corp.) immersed in solutions ranging from 0 to 100% contrast. The images were then reviewed in a blinded fashion by a panel of 9 endoscopists with experience using the SpyGlass?system. The reviewers scored the quality of each image based on a scale of 0 (extremely poor) to 10 (excellent). Results: With the cholangioscope immersed in saline and 100% contrast, the mean image quality scores were 7.6 (95% confi dence interval [CI], 6.7-8.5) and 6.9 (95% CI, 5.8-8.0), respectively. The highest mean image quality score was 7.8 (95% CI, 6.7-8.9), obtained in 70% contrast. No signifi cant difference was noted in mean image quality scores using a one way analysis of variance technique (p=0.414). Conclusions: Although there are limitations to ex vivo studies, we encourage endoscopists to use intraductal contrast prior to peroral cholangioscopy, if needed for lesion localization. (Gut Liver 2011;5:115-116)
Keywords: Bile ducts; Endoscopes; Cho langiopancreatography; Endoscopic retrograde
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