Gut and Liver https://doi.org/10.5009/gnl18579 The Role of Intestinal Fungi and Its Metabolites in Chronic Liver Diseases
Author Information
Ningning You1 , Lili Zhuo1 , Jingxin Zhou1 , Yu Song2 , and Junping Shi3
1Department of Liver Diseases, The Affiliated Hospital of Hangzhou Normal University, 2Department of Liver Diseases, Zhejiang Chinese Medical University, and 3Department of Liver Diseases, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China

Junping Shi
Department of Liver Diseases, The Affiliated Hospital of Hangzhou Normal University, 126 Wenzhou Road, Hangzhou 310015, China
Tel: +86-57188358060, Fax: +86-57188021730, E-mail: 13957121199@126.com
© The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. All rights reserved.

Abstract
Current studies have confirmed that liver diseases are closely related to intestinal microorganisms; however, those studies have mainly concentrated on bacteria. Although the proportion of intestinal microorganisms accounted for by colonizing fungi is very small, these fungi do have a significant effect on the homeostasis of the intestinal microecosystem. In this paper, the characteristics of intestinal fungi in patients with chronic liver diseases such as alcoholic liver disease, nonalcoholic fatty liver disease and cirrhosis are summarized, and the effects of intestinal fungi and their metabolites are analyzed and discussed. It is important to realize that not only bacteria but also intestinal fungi play important roles in liver diseases.
Keywords: Intestinal fungi; Alcoholic liver disease; Cirrhosis; Non-alcoholic fatty liver disease
Abstract
Current studies have confirmed that liver diseases are closely related to intestinal microorganisms; however, those studies have mainly concentrated on bacteria. Although the proportion of intestinal microorganisms accounted for by colonizing fungi is very small, these fungi do have a significant effect on the homeostasis of the intestinal microecosystem. In this paper, the characteristics of intestinal fungi in patients with chronic liver diseases such as alcoholic liver disease, nonalcoholic fatty liver disease and cirrhosis are summarized, and the effects of intestinal fungi and their metabolites are analyzed and discussed. It is important to realize that not only bacteria but also intestinal fungi play important roles in liver diseases.
Keywords: Intestinal fungi; Alcoholic liver disease; Cirrhosis; Non-alcoholic fatty liver disease
Search for
Services
Archives