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Fig. 2. Inflammatory cell recruitment and localization around lipid-laden hepatocytes in HF-fed foz/foz mice with non-alcoholic steatohepatitis (NASH). (A) H&E-stained liver section from HF-fed (0.2% cholesterol) foz/foz mouse with NASH, showing several enlarged hepatocytes with macrosteatotic vacuoles, and at least one ballooned hepatocyte (bottom right). (B) Macrophages (F4/80 positive), and (C) neutrophils (myeloperoxidase positive) accumulate around hepatocytes showing macrosteatotic vacuoles. These livers contain large amounts of free cholesterol.115 Scale bars represent 20 ?m.
Gut Liver 2012;6:149~171 https://doi.org/10.5009/gnl.2012.6.2.149
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