Gut and Liver

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Pseudoinvasion in an Adenomatous Polyp of the Colon Mimicking Invasive Colon Cancer

Tae Jun Byun*, Dong Soo Han*, Sang Bong Ahn*, Hyun Seok Cho*, Chang Soo Eun*, Yong Cheol Jeon*, Joo Hyun Sohn*, and Young-Ha OhΆΣ
Departments of *Gastroenterology and ΆΣPathology, Hanyang University College of Medicine, Guri Hospital, Guri, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Pseudoinvasion or pseudocarcinomatous invasion in an adenomatous polyp of the colon can be unfamiliar to an endoscopist. Pseudoinvasion in an adenomatous polyp represents prolapse of the adenomatous epithelium into its stalk. In most cases its morphology does not differ from of general adenomatous polyps, but in some cases it can morphologically mimic a malignant polyp with submucosal invasion due to mass- like lesioning of its stalk. This makes it difficult for endoscopists to differentiate pseudoinvasion in an adenoma from an invasive carcinoma by conventional endoscopy; instead, endoscopic ultrasonography can provide useful information for differentiating these conditions. We report on an 82-year-old man who presented with a large pedunculated polyp with a thick stalk in the sigmoid colon, which mimicked a submucosal invasive carcinoma. The patient was diagnosed with pseudoinvasion in an adenomatous polyp after segmental resection of the sigmoid colon. (Gut and Liver 2009;3:130-133)
Pseudoinvasion; Adenomatous polyps; Malignant polyp; EUS
Gut and Liver 2009 Jun; 3(2): 130-133
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